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Musculoskeletal: Neck & Upper Extremity - Rotator Cuff Impingement
1. Diagnosis Overview and Risk Factors
Compression of rotator cuff tendons between humeral head and acromion
Common in middle-aged adults, overhead athletes, and manual laborers
Risk factors include repetitive overhead activity, poor posture, acromial spurs
2. Patient Presentation
Lateral shoulder pain worsened with overhead motion or at night
Decreased active range of motion due to pain
Positive Neer and Hawkins-Kennedy tests
3. Diagnosis & Workup
Primarily a clinical diagnosis: X-ray may show acromial morphology or spurs, MRI if concern for rotator cuff tear
4. Management
Activity modification and physical therapy
NSAIDs or acetaminophen Subacromial corticosteroid injection
Surgery for refractory cases
5. Complications
Progression to rotator cuff tear, Chronic pain and loss of shoulder function
Musculoskeletal: Neck & Upper Extremity - Osteoarthritis
1. Diagnosis Overview and Risk Factors
Degenerative joint disease with cartilage breakdown
Increased prevalence with age, obesity, joint overuse, prior injury
2. Patient Presentation
Joint pain worse with activity and relieved by rest
Morning stiffness lasting less than 30 minutes
Crepitus and decreased range of motion
3. Diagnosis & Workup
Clinical diagnosis supported by imaging
X-ray shows joint space narrowing, osteophytes, subchondral sclerosis
4. Management
Weight loss and exercise NSAIDs or topical analgesics Intra-articular steroid injections, Joint replacement for severe disease
5. Complications
Progressive functional decline, Chronic pain and disability
Musculoskeletal: Back & Lower Extremity - Ankylosing Spondylitis
1. Diagnosis Overview and Risk Factors
Chronic inflammatory spondyloarthropathy affecting the spine
Typically affects young adult males
Associated with HLA-B27
2. Patient Presentation
Inflammatory back pain improving with activity
Morning stiffness lasting over 30 minutes
Limited spinal mobility
3. Diagnosis & Workup
Elevated ESR/CRP X-ray or MRI showing sacroiliitis
HLA-B27 supportive but not diagnostic
4. Management
NSAIDs as first-line therapy TNF-alpha or IL-17 inhibitors Physical therapy and posture training
5. Complications
Spinal fusion and kyphosis, Restrictive lung disease
Musculoskeletal: Back & Lower Extremity - Osteoporosis
1. Diagnosis Overview and Risk Factors
Systemic skeletal disease with low bone mass Common in postmenopausal women and older adults Risk factors include steroid use, smoking, low BMI
2. Patient Presentation
Often asymptomatic until fracture occurs Back pain or height loss from vertebral fractures
3. Diagnosis & Workup
DXA scan showing T-score ≤ -2.5 Evaluate secondary causes with labs if indicated
4. Management
Calcium and vitamin D supplementation Bisphosphonates or other antiresorptive agents Fall prevention strategies
5. Complications
Fragility fractures, Increased morbidity and mortality
Peripheral Nervous System - Carpal Tunnel Syndrome
1. Diagnosis Overview and Risk Factors
Median nerve compression at the wrist Associated with repetitive wrist use, pregnancy, diabetes
2. Patient Presentation
Numbness and tingling in thumb, index, and middle fingers Symptoms worse at night Positive Phalen and Tinel signs
3. Diagnosis & Workup
Clinical diagnosis Nerve conduction studies for confirmation or surgical planning
4. Management
Wrist splinting NSAIDs or corticosteroid injection Surgical decompression if severe
5. Complications
Permanent median nerve damage Thenar muscle atrophy
Peripheral Nervous System - Guillain-Barré Syndrome
1. Diagnosis Overview and Risk Factors
Acute inflammatory demyelinating polyneuropathy - Often follows viral or gastrointestinal infection
2. Patient Presentation
Ascending symmetric weakness, Areflexia
3. Diagnosis & Workup
Clinical diagnosis, LP for CSF showing inc proteins, EMG
4. Management
IVIG or plasmapheresis Supportive care and respiratory monitoring
5. Complications
Respiratory failure Autonomic dysfunction
Central Nervous System - Febrile Seizure
1. Diagnosis Overview and Risk Factors
Seizure associated with fever in children aged 6 months to 5 years Often triggered by viral infections
2. Patient Presentation
Generalized tonic-clonic seizure with fever Rapid return to baseline neurologic status
3. Diagnosis & Workup
Clinical diagnosis No routine imaging or EEG for simple febrile seizures
4. Management
Parental reassurance Antipyretics for comfort No chronic anticonvulsants
5. Complications
Recurrence Low risk of epilepsy
Central Nervous System - Hyperprolactinemia
1. Diagnosis Overview and Risk Factors:
Elevated prolactin levels due to pituitary adenoma or medications
Associated with dopamine antagonist use
2. Patient Presentation
Galactorrhea Amenorrhea or infertility Decreased libido
3. Diagnosis & Workup
Elevated serum prolactin level Pituitary MRI if persistent elevation
4. Management
Dopamine agonists (cabergoline, bromocriptine) Surgery for refractory macroadenomas
5. Complications
Hypogonadism
Bone loss