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Homeostasis
the process of living organisms and systems trying to stay at a set point or set range
Negative feedback
output of a system counteracts the initial change, reverses the change
What does it mean that the body is in dynamic equilibrium?
It is stable, but constantly adjusting
Thermoregulation
Control of body temperature
What is osmoregulation?
Control of water and salt balance in the body
What is a set point?
The target value of a physiological condition maintained by homeostasis
What is a stimulus?
Any change that moves conditions away from the set point
What environments can a stimulus come from?
Internal environment (ex. rising blood sugar) or external environment (ex. cold weather)
What are the 4 parts of a feedback system?
Receptor, Control center, Effector, Response
What does a receptor (sensor) do?
Detects changes in the environment
What is the control center?
The part of the body (usually the brain or an endocrine gland) that receives information and decides what action to take and then sends instructions
What is an effector?
An organ or tissue that carries out the response
What is a response?
The change caused by the effector that moves the body back toward the set point
What are ectotherms?
Animals that rely mainly on environmental heat sources to regulate body temperature
How do ectotherms regulate temperature?
Through behavior (ex. basking in the sun or moving underground)
What are endotherms?
Animals that rely on internal heat production to maintain body temperature
How do endotherms generate heat?
Shivering, increasing metabolism, and burning stored energy
What is shivering?
Involuntary muscle contractions that produce heat
What causes goosebumps?
Arrector pili muscles pulling hairs upright
How does fat help with temperature regulation?
Fat under the skin reduces heat loss
How do both ectoderms and endotherms help regulate temperature internally?
By adjusting blood flow through the circulatory system
What is vasodilation?
Blood vessels widen, more warm blood moves to skin allowing heat to escape to skin
What is the result of vasodilation?
Cooling of body
What is vasoconstriction?
Blood vessels narrow to conserve heat
What is vasoconstriction?
Blood vessels narrow to conserve heat, less blood reaches skin, keeps heat in core organs
What is the hypothalamus in relation to temperature?
The brain’s temperature control center
What does the hypothalamus do during a fever?
Raises the body’d temperature set point
Why is fever helpful?
Higher temperature slows bacteria and boosts immune fuction
What are electrolytes?
Salts that form ions in water (Na+, K+)
What are nonelectrolytes?
Substances that do not form ions (ex. glucose)
Why are electrolytes important?
They control nerve signals, muscle contraction, blood pressure, and fluid movement
What is interstitial fluid?
Fluid between cells similar to blood plasma but with fewer proteins
What is a semipermeable membrane?
A membrane that allows some substances to pass but blocks others
What can move across semipermeable membranes?
Water and some substances
What cannot freely pass semipermeable membranes?
Many solutes (like certain ions)
How does the body gain water?
Drinking and eating
How does the body lose water?
Sweating, urinating, breathing, and feces
Why must osmoregulation constantly occur?
Because the body continuously gains and loses water
What happens if you don’t drink enough water?
The kidneys conserve water and produce concentrated urine to reduce water loss
What happens if you drink too much?
Kidneys remove extra water and urine becomes more diluted
What is the function of the excretory system?
To remove metabolic waste and maintain internal balance
What are the main functions of the kidneys?
Filter blood and regulate water and salt balance
What structures inside kidneys filter blood?
Nephrons
What is a nephron?
The functional filtering unit of the kidney
What is a nephron?
The functional filtering unit of the kidney
What do nephrons produce?
Urine
Where does the urine go after it forms in the kidneys?
It travels through ureters, is stored in the bladder, and exits via the urethra
What is the renal cortex?
The outer kidney layer where blood filtering begins and nephrons are located
What is the renal medulla?
The middle layer of kidney containing tubes that help concentrate urine
What is the renal pelvis?
A funnel-shaped area that collects urine and connects to the ureter (last kidney layer)
What is a ureter?
A tube that carries urine from the kidney to the bladder
What is the urinary bladder?
The organ that stores urine before excretion
What is the blood flow pathway to the kidneys?
Heart → aorta → renal artery → smaller vessels → nephrons
What is the renal artery?
The artery that delivers blood to the kidney
Why do kidneys constantly receive blood?
To continuously filter and clean
How many major steps are involved in nephron filtration?
Three steps: filtration, reabsorption, and secretion
Where does filtration occur in the nephron?
At the glomerulus
What is the glomerulus?
A bundle of tiny capillaries where blood filtration begins
What leaves the blood during filtration?
Water, ions, and wastes
Do useful substances leave the blood during filtration?
Yes, useful substances temporarily leave as well
Where do filtered substances go after leaving the blood?
Into the nephron tubule
What is reabsorption?
The process of returning useful substances from the tubule back into the blood
What substances are reabsorbed?
Most water, needed ions, glucose, and nutrients
Why is reabsorption important?
It prevents loss of useful materials
Does reabsorption require energy?
Some reabsorption uses ATP
What is secretion in the nephron?
The active movement of additional wastes from blood into the tubule
What is the purpose of secretion?
To add more waste to urine
What happens after blood is filtered?
Clean blood leaves the kidney
What is the pathway of cleaned blood leaving the kidney?
Kidney → renal vein → inferior vena cava → heart
What is the renal vein?
The vein that drains filtered blood from the kidney
What becomes urine?
Remaining fluid in the tubules after filtration, reabsorption, and secretion
What does urine contain?
Water, wastes, and excess ions
What do stretch receptors in the bladder do?
Detect fullness
What happens when the bladder becomes full?
Nerves send signals to the brain, creating the urge to urinate
Why doesn’t urine leak out constantly?
Sphincter muscles stay closed
What happens when you decide to urinate?
The brain signals sphincters to relax
What are sphincters?
Muscle rings that control urine release
What is the urethra?
The tube that carries urine from the bladder to the outside of the body
What are blood vessels?
Tubes that transport blood and dissolved substances throughout the body
What do arteries do?
Carry blood away from the heart
What do veins do?
Carry blood toward the heart
What happens when body temperature drops too low?
Blood vessels constrict, sweating stops, and shivering begins
What happens when body temperature rises too high?
Blood vessels dilate and sweat production increases
Where is the body’s temperature “thermostat” located?
The hypothalamus in the brain
What is an example of a solute?
Salt
What is an example of a solvent?
Water
What is an example of a solution?
Salt-water (mixed together)
What is the intracellular compartment?
Fluid inside cells
What is the interstitial compartment?
Fluid between cells
What is blood plasma?
The watery fluid portion circulating in blood vessels
What systems are part of the excretory system?
Urinary system, skin (sweat), and respiratory system
Which sphincter is involuntary?
Internal urethral sphincter
Which sphincter is voluntary and conscious?
External urethral sphincter
What triggers the urge to urinate?
Stretch receptors in the bladder wall sending signals to the brain and spinal cord