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what are 2 broad categories of pulmonary disease
restrictive and obstructive
Restrictive lung disease mainly causes trouble with what?
inhalation
A common finding in restrictive lung disease?
hypoxemia
How is hypoxemia seen numerically?
low SO2 and/or low PO2
what does V stand for
ventilation
what does Q stand for
perfusion
what is a normal V/Q ratio
about 0.8
What is V/Q mismatch?
when the V/Q ratio is not normal
What test can measure V/Q mismatch?
V/Q scan
Low V/Q means what?
less ventilation than normal
high V/Q means what
less perfusion than normal
Low V/Q disorders have a problem with what?
getting air to the alveoli
What are examples of chest wall restriction?
Kyphosis, obesity, neuromuscular weakness
What diseases can cause neuromuscular weakness and restriction?
polio and myasthenia gravis
What can cause airway restriction?
foreign body, tumors, airway inflammation
What is stridor?
a high-pitched raspy sound on inspiration
what causes stridor
narrowed inflamed upper airways
what is croup
inflammation of the larynx, trachea, and bronchi
who commonly gets croup
infants and very young children
classic signs of croup
fever, increased RR, barking cough, stridor
treatment for croup
cool mist and sometimes steroids
What is pleural effusion?
extra fluid in the pleural space
What can cause pleural effusion?
Cancer, infection, inflammation, heavy coughing
What is pleuritic pain?
Chest pain with deep breathing, coughing, or movement
Why do respirations become shallow with pleural effusion?
Because of pain and fluid buildup
What is pneumothorax?
air in the pleural space
Why is pneumothorax a problem?
It destroys normal negative pressure and the lung can collapse
Main symptoms of pneumothorax?
chest pain and SOB
What is a traumatic pneumothorax?
Pneumothorax caused by injury
What is a spontaneous pneumothorax?
Pneumothorax that happens without trauma
Who is at risk for spontaneous pneumothorax?
Tall, thin smokers or people with lung disease
What is tension pneumothorax?
Air enters the pleural space but cannot get out
Why is tension pneumothorax dangerous?
It can affect the other lung and lower cardiac output
Basic treatment for pneumothorax?
re-establish negative pressure
How is negative pressure restored in pneumothorax?
with a chest tube
What is a water seal drainage system?
a system where water acts like a one-way valve for air
What is pneumonia?
An acute infection of the lower respiratory tract
What organisms can cause pneumonia?
bacteria, viruses, fungi, parasites
Who is at higher risk for pneumonia?
Very young, elderly, immunocompromised, smokers, immobilized
What are the 3 main types of pneumonia?
CAP, nosocomial, aspiration
What does CAP stand for?
Community-acquired pneumonia
CAP is often called what?
Walking pneumonia
What is nosocomial pneumonia?
Hospital-acquired pneumonia
Nosocomial pneumonia is often caused by what?
More virulent organisms, often gram-negative
What is aspiration pneumonia?
Pneumonia caused by inhaling something into the lungs
Who is at risk for aspiration pneumonia?
People with weak gag, cough, or swallow reflexes
Examples of aspiration pneumonia risk?
Elderly, alcohol intoxication, brain injury, post-seizure
What are infiltrates in pneumonia?
Inflammatory/infectious debris in alveoli and tissue
What is atelectasis?
Collapse of alveoli
Why does atelectasis happen in pneumonia?
Mucus/inflammation blocks airflow, so alveoli collapse
What is consolidation?
Infiltrates + atelectasis
What does consolidation do to the lung?
Makes it stiff and less functional
What is lobar pneumonia?
Pneumonia in one lobe
What is bronchopneumonia?
More diffuse/spread-out pneumonia
Common symptoms of pneumonia?
Fever, chills, malaise, pleural pain, cough, dyspnea
What lung sound may be heard in pneumonia?
crackles
Why might breath sounds be decreased in pneumonia?
Consolidated lung tissue has less air movement
What test often looks abnormal in pneumonia?
chest x-ray
How is pneumonia diagnosed?
Chest x-ray, gram stain, sputum culture
How is pneumonia treated?
Antibiotics, hydration, pulmonary toilet
What is pulmonary toilet?
Coughing, turning, deep breathing, suctioning
What is pulmonary edema?
Too much fluid in the alveoli
What are the 2 main types of pulmonary edema?
Cardiogenic and noncardiogenic
What causes noncardiogenic pulmonary edema?
Damage to capillary endothelium
What can damage capillary endothelium and cause noncardiogenic pulmonary edema?
Smoke inhalation or other harmful substances
What happens after capillary injury in noncardiogenic pulmonary edema?
Capillary permeability increases
What leaks into the alveoli in noncardiogenic pulmonary edema?
Fluid and plasma proteins
How does pulmonary edema damage alveoli further?
It damages cells that make surfactant
Why is loss of surfactant bad?
It causes atelectasis
What is atelectasis?
Collapsed alveoli
Why does atelectasis lower oxygenation?
Collapsed alveoli are not available for gas exchange
Common signs of pulmonary edema?
Cough, dyspnea, crackles, pink frothy sputum, hypoxemia
What are 2 causes of atelectasis in these notes?
Mucus blockage and loss of surfactant
How can pneumonia cause atelectasis?
Mucus blocks air flow, so alveoli collapse
How can edema cause atelectasis?
It damages surfactant-making cells, causing alveolar collapse
What is another name for lung cancer
Bronchogenic carcinoma
Where does bronchogenic carcinoma arise from?
The epithelium of the respiratory tract
What is the most common cause of lung cancer?
Cigarette smoking
How does smoking cause lung cancer?
Tobacco carcinogens cause genetic mutations in bronchial cells
What procedure is used to help diagnose lung cancer?
bronchoscopy
What are the 2 main lung cancer types in these notes?
Small cell (SCLC) and non-small cell (NSCLC)
Common signs of lung cancer?
Pleural effusion, cough, sputum, chest pain, SOB, weight loss, anorexia
High V/Q means what kind of problem?
low perfusion
In high V/Q, what is the issue?
Air is present, but not enough blood gets to it
What can cause high V/Q besides emboli?
Vessel strictures, malformations, birth defects
What can a pulmonary embolus be made of?
Blood clot, tissue fragment, or air bubble
What are the 3 parts of Virchow’s triad?
Endothelial injury, hypercoagulability, venous stasis