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What is resting membrane potential?
The charge difference when the neuron is inactive
What is the typical resting value?
About -70 mV
What is depolarization?
A decrease in membrane potential (more positive)
What causes depolarization?
Increased Na+ or Ca2+ entry or decreased K+ movement out
What is hyperpolarization?
An increase in membrane potential (more negative)
What causes hyperpolarization?
Increased K+ leaving or Cl- entering the cell
Why is resting potential important?
It allows neurons to respond to stimuli
What is a graded potential?
A small, local change in membrane potential
What happens to graded potentials over distance?
They decrease in strength
Can graded potentials add together?
Yes, they can summate
What is an action potential?
A large signal that travels across the entire membrane
What triggers an action potential?
Reaching threshold
What is threshold?
The minimum stimulus needed to trigger an action potential
What does all-or-none mean?
The action potential occurs fully or not at all