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neurons
specialized cells that make up nervous system
cell body
contains nucleus aka soma
dendrites
branches // receive signals
axon
conduct electrical impulses
axon terminals
send signal to other cells
glial cells
hold neuron in place // make nutrients
neuron function 1
generate electricity - create nerve impulses
neuron function 2
release chemicals // communicate with other cells
neural impulse
aka action potential
resting potential
V= -70mV
action potential definition
depolarized // V= +40mV
how does action potential happen
Na+ channels open and Na+ enter
depolarized meaning
becomes less negative
How does restoring resting potential happen
Na+ channels close and K+ channels open
hyperpolarization
becomes more negative
absolute refractory period
cell will NOT fire again // limits how often impulses occur
the all or none law
action happens occur at max intensity OR not at all
stronger neural signal =
creates more action potential
stronger action potential
myelin sheath
made from glial cells // insulation = faster
nodes of ranvier
absence of myelin sheath // signals can “skip”
synapse
communicates across gaps // synaptic cleft
neurotransmitter
chemical substance that carries messages
synapse step 1
synthesis of neurotransmitters
synapse step 2
storage // held in synaptic vessels until needed
synapse step 3
released into synaptic space
synapse step 4
binding // attach to receptor sites
synapse step 5
deactivation // stop neurotransmitter signals
excitatory neurotransmitter
increase resting potential by depolarizing
inhibitory neurotransmitter
decrease resting potential by hyper polarization
glutamate
excitatory: learning and memory (controls behaviour)
acetylcholine
excitatory: muscle movement and memory
GABA
inhibitory: anxiety and motor control (controls behaviour)
Serotonin
inhibitory: mood, eating, and sleep
endorphins (adrenaline)
inhibitory: controls sensitivity to pain
norepinephrine
excitatory and inhibitory: wakefulness and memory (learning)
dopamine
excitatory and inhibitory: voluntary movement and pleasure (motivation)
sensory neurons
carry input from sense organs to spinal cord and brain // PNS → CNS
motor neurons
transmit impulses from brain and spinal cord to muscles and organs // CNS → PNS
interneurons
receives information and relays it to the CNS
Peripheral nervous system
Somatic and Autonomic
somatic nervous system
sensory and motor neurons // voluntary movements and sense
autonomic nervous system
involuntary movement and functions
where does sympathetic and parasympathetic belong to
autonomic nervous system
somatic nervous system
sympathetic nervous system
fight or flight
parasympathetic nervous system
rest and digest
Central Nervous System (CNS)
Spinal cord and brain
Spinal cord
Connects parts of PNS with brain
Spinal reflexes
Stimulus- response sequence // no brain involvement
Forebrain
Highly developed, numerous functions
Midbrain
Reflexes and voluntary movements
Hindbrain
Vital functions and coordinating movements
Parts of Forebrain (aka cerebrum)
cerebral cortex
Basal ganglia
Limbic system
Thalamus
Hypothalamus
Cerebral cortex
outer layer of hemispheres (occipital, temporal, frontal, and parietal) // involved in thinking
Basal Ganglia
Collections of neurons needed for motor function
Hippocampus (limbic system)
Memory
Amygdala (limbic system)
Emotional response
Nucleus accumbens (limbic system)
Reward center
Thalmus
Relays sensory information
Hypothalamus
Regulate basic biological drives // homeostasis
Parts of Midbrain
Reticular formation
Superior colliculi
Inferior colliculi
Reticular formation
Regulates consciousness
Superior colliculi
Involved in vision
Inferior colliculi
Involved in hearing
Parts of Hindbrain (aka brainstem)
Medulla
Pons
cerebellum
medulla
controls automatic life-sustaining functions (ie breathing, digestion, heart)
pons
relay station for signals // regulate sleep and controls muscle/ glands in face
cerebellum
controls procedural memory (ie motor skills)
motor cortex
controls voluntary movements
Where is motor cortex located
Frontal lobe
somatic sensory cortex
receives input (sensations)
Where is somatic sensory cortex located
Parietal lobe
primary auditory cortex
temporal lobe of both hemispheres
Where is primary auditory cortex located
Temporal lobe
primary visual cortex
occipital lobe of both hemispheres
Where is primary visual cortex located
Occipital lobe
wernicke’s areas (speech)
language comprehension
Where is wernicke’s area located
Left side of temporal lobe
Broch’s area
speech production/ formation
Where is Broca’s area located
Left side of frontal lobe
Association cortex
all the other lobes of cerebral cortex
Right hemisphere
creativity - controls left side of body
Left hemisphere
analytical thinking- controls right side of body
corpus callous
bridges the hemispheres together
frontal lobe
personality and motor
parietal lobe
sensation
temporal lobe
hearing
occipital lobe
vision
EEG
measures changes in brain activity with electrodes
EEG’s are
cheap and quick
CT
takes horizontal pictures of the brain with x-rays
CT’s are
cheap and quick
PET
measure brain activity with radioactive liquid
PET’s are
cheap and quick
MRI
take a high quality picture of the brain with magnets
MRI’s are
expensive
fMRI
measure change in activity thorough O2 levels
fMRI’s are
expensive
DTI
uses an MRI to build a picture