Reproductive hormones summary

Where is GnRH secreted from?

hypothalamus

What does GnRH act on?

anterior pituitary (same in males and females)

What is the action of GnRH?

Release of FSH and LH (same in both males and females)

Where is LH secreted from?

anterior pituitary

What does LH act upon in males?

the testis - leydig cells

What is the action of LH in males?

stimulates testosterone formation

What does LH act upon in females?

Ovaries - cells of theca interna and luteal cells

What is the action of LH in females?

Stimulates ovulation, formation of CL and progesterone secretion

Where is FSH secreted from?

anterior pituitary

What does FSH act upon in males?

Testis- Sertoli cells

What is the acton of FSH in males?

Sertoli cell function

What does FSH act upon in females?

Ovaries - granulose cells

What is the action of FSH in females?

Follicular development and Oestrogen synthesis

Where is Oestrogen secreted from in males?

Sertoli cells of testis

Where is Oestrogen secreted form in females?

Granulose cells of follicle

What does oestrogen at upon in females?

Hypothalamus, entire repro tract and mammary glands

What is the action of oestrogen in females?

Sexual behaviour, GnRH elevated secretory activity of whole reproductive tract, enhanced uterine motility

Where is progesterone secreted from?

corpus luteum and placenta

Is progesterone found in males as well as females?

no

What does progesterone act upon?

Uterine endometrium, mammary gland, myometrium and hypothalamus

What is the action of progesterone?

Endometrial secretion, inhibits GnRH release, inhibits reproductive behaviour, promotes maintenance of pregnancy

Where is testosterone secreted from?

Leydig cells of testes

Cells of theca interna in females

What does testosterone act upon in males?

accessory sex glands, tunica darts of scrotum, seminiferous epithelium, skeletal muscle

What is the action of testosterone?

anabolic growth, promotes spermatogenesis, promotes secretion of accessory sex glands

Where is Prostaglandin F2⍺ secreted from?

Uterine endometrium

What does Prostaglandin F2⍺ act upon?

Corpus luteum, uterine myometrium

What is the action of Prostaglandin F2⍺?

Leutyolysis, promotes uterine tone and contraction

Where is Inhibin secreted from?

Granulose cells (female)

Sertoli cells (male)

What does inhibit act upon?

Anterior pituitary (both males and females)

What is the action of Inhibin?

inhibits FSH secretion (both males and females)

Where is prolactin secreted from?

anterior pituitary

What does prolactin act upon?

Testes and brain (males)

Mammary cells (female)

What is the action of prolactin?

Lactation and maternal behaviour

(can induce maternal behaviour in males too)