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Sleep
Periodic natural loss of conciousness
Circadian rhythm
Regular bodily rhythms that occur in 24 hour cycle (Our biological clock)
Examples of circadian rhythm
Body temperature, thinking, memory
REM sleep characteristics
Rapid eye movement, vivid dreams, muscles relaxing, active body system. Gets longer as night progress. Sleep paralysis can occur in this stage
Alpha waves
Slow brain waves of a relaxed awake state
NREM sleep
non-rapid eye movement sleep, every other sleep stage other than REM
Hallucinations
False sensory experiences
Hypnagogic sensations
Bizarre feeling such as falling or floating while transitioning to sleep
Delta Waves
Large slow brain waves associated with deep sleep of NREM-3
Suprachiasmatic Nucleus (SCN)
Pair of cell clusters in the hypothalamus that controls circadian rhythm
NREM-1 characteristics
Hypnagogic sensations and hallucinations,
NREM-2 characteristics
Sleep spindles, stage gets longer as night goes on
NREM-3 characteristics
Delta waves, grows shorter and disappears as night goes on
Sleep paralysis causation
Motor cortex is active, but brainstem blocks it’s messages
Melatonin production is (increased/d
Melatonin production is (increased/decreased) in the night
Increased
Why do we sleep?
Protection
Immune system restoration and repair brain tissue
Restore and rebuild fading memories
Feeds creative thinking
Supports growth
Insomnia
Recurring problems in falling asleep or staying asleep
Narcolepsy
Sudden attacks of heavy sleepiness often triggered by strong emotions
Sleep apnea
Stopping breathing while sleeping
Sleepwalking
doing normal waking activities while asleep
When does sleepwalking occur?
NREM-3
When does sleeptalking occur?
Any sleep stage
Night terror
Appearing terrified, talking nonsense, or walking around during NREM-3 sleep (NOT THE SAME AS NIGHTMARES)
Effects of insomnia
Chronic tiredness, reliance on alcohol or sleeping pills, reduced REM sleep
Effects of sleep apnea
Fatigue and depression, associated with obesity especially among men
Effects of night terrors
Doubling of child’s heart and breathing rate during the attack

Dream
Sequence of images, emotion, and thoughts passing through a sleeping person’s mind
Manifest content
Remembered storyline of a dream (According to Freud)
Latent content
underlying meaning of a dream (According to Freud)
REM rebound
tendency for REM sleep to increase following REM sleep deprivation
Psychoactive drug
Chemical substance that alters perception and mood
Substance use disorder
Disorder characterized by continued substance use despite significant life disruption
Tolerance
Brain’s chemistry adapts to offset drug effect, leading to larger doses required to experience same effect
Withdrawal
Discomfort following discontinuing addictive drug or behavior
Depressants
Reduces neural activity and slow body function
Barbiturates
Drugs that depress CNS, reduces anxiety but impairs memory and judgement
Opiates
Depresses neural activity, temporarily lessens pain and anxiety
Stimulant
Drug that excite neural activity and speed up body function
Nicotine
A stimulating and highly addictive psychoactive drug
Cocaine
Powerful and addictive stimulant derived from coca plant
Amphetamines
Drugs that stimulate neural activity, causing accelerated body functions and associated with energy and mood changes
methamphetamine
drug that stimulates the CNS with accelerated body functions and associated energy and mood changes; reduces baseline dopamine levels
Ecstasy (MDMA)
Synthetic stimulant and mild hallucinogen
Near death experience
Altered level of conciousness after a close brush with death
LSD
powerful hallucinogenic drug also known as acid
THC
Major ingredient in marijuana, triggers effects such as mild hallucinations
Alcohol (type, positive/negative effects)
Depressant
Positive effects: initial high followed by relaxation
Negative effects: Impulsive behavior, depression, memory loss, organ damage, impaired reactions
Heroin (type, positive/negative effects)
Depressant
Positive effects: Rush of euphoria, pain relief
Negative effects: Depressed physiology, agonizing withdrawal
Caffeine (type, positive/negative effects)
Stimulant
Positive effects: Increased alertness and wakefulness
Negative effects: Anxiety, restlessness, insomnia, uncomfortable withdraw
Nicotine (type, positive/negative effects)
Stimulant
Positive effects: Arousal and relaxation, sense of well being
Negative effects: Heart disease, cancer
Cocaine (type, positive/negative effects)
Stimulant
Positive effects: Rush of euphoria, confidence, energy
Negative effects: Cardiovascular stress, paranoia, depressive crash
Methamphetamine (type, positive/negative effects)
Stimulant
Positive effects: Euphoria, alertness, energy
Negative effects: Irritability, insomnia, hypertension, seizures
Ecstasy (type, positive/negative effects)
Stimulant, mild hallucinogen
Positive effects: emotional elevation
Negative effects: impulsive behavior, dehydration, overheating, depressed mood, impaired cognitive and immune functioning
LSD (type, positive/negative effects)
Hallucinogen
Positive effects: visual “trip”
Negative effects: Risk of panic
Marijuana (type, positive/negative effects)
Mild Hallucinogen
Positive effects: Enhanced sensation, pain relief, time distortion, relaxation
Negative effects: Impaired learning and memory, increased risk of psychological disorders
Sensory Neurons
Input source of the body, connects the sensory receptors to the central nervous system
Why do reflexes happen?
Sensory neurons send a message to the interneuron in the spinal cord, which sends a motor neuron to the muscles. The signal does not reach the brain.
MEG scan
Uses large magnets to recieve images of internal organs in the body
Motor Neurons
Output source of the body, connects the central nervous system to muscle glands
Interneuron
Facilitates communication in the CNS (only operates in the CNS)
Dendrites
Neuron extensions that receive and integrate messages
Axon
Neuron extension that passes messages through branches to other neurons, muscles, or glands
myelin
Tissue layer encasing axons, greatly increases transmission speed
Glial cells
Cells that support and protect neurons. Plays role in learning, thinking, and memory
Oligodendroglia
Glia cells that produce myelin in the central nervous system
Schwann cells
Glial cells that produce myelin in the peripheral nervous system
Astrocytes
Star shaped, forms a lot of the matrix and envelops blood vessels
Matrix
substance that occupies empty space between cells
Nodes of Ranvier
Spaces between myelin cells, keeps charges moving through the axon. Without them, charges might lose intensity
Multiple sclerosis
Damage that develops on the myelin sheaths of axon bundles in the brain, spinal cord, and optic nerves, caused by genetics and the environment
Symptoms of multiple sclerosis
muscular weakness, lack of coordination, vision problems
Guillain-Barré Syndrome
an immune response where the body attacks the myelin of peripheral nerves (skin + muscles), usually occurs after microbial infection
Symptoms of Guillain-Barré Syndrome
fever and nausea, progressing to lower extremity muscular weakness, moving upwards eventually causing numbness and paralysis
Synapse
The place where the axon tip of sending neuron and cell body of receiving neuron meet
All or none response
Neuron’s reaction of either firing with full strength or not firing at all (pressing trigger harder won’t increase speed of bullet)
Threshold
Level of stimulation needed to trigger a neural impulse (lightly pressing trigger wont shoot the gun)
neural impulse
Electrical charge that travels down an axon
refractory period
Pause after neuron has fired, impulses cannot continue until axon returns to resting state (Gun has to reload before being able to fire again)
Neurotransmitters
Messengers that cross gaps between neurons and bind to receptor sites. Influences whether neuron will generate an impulse
Acetylcholine (ACh) function and example of malfunction
Enables muscle action, learning, and memory. Alzheimer’s disease can lead to ACh producers deteriorating
Dopamine function and example of malfunction
Neurotransmitter that influences movement, learning, attention, and emotion. Too much has been linked to schizophrenia while too little has been linked to tremors and decreased mobility in Parkinson’s disease
Serotonin function and example of malfunction
Neurotransmitter that affects mood, hunger, sleep, and arousal. Too little has been linked to depression while too much has been linked to drug reactions which can be dangerous
Norepinephrine function and example of malfunction
Neurotransmitter that helps control alertness and arousal, triggers the flight or fight response. Too little can depress mood
GABA (gamma-aminobutyric acid) function and example of malfunction
Neurotransmitter that slows down brain activity by blocking certain signals. Regulates anxiety, muscle relaxation, and sleep. Undersupply can lead to seizures, tremors, and insomnia while oversupply can impair cognitive function
Glutamate function and example of malfunction
Neurotransmitter that plays a role in learning and memory. Too much can overstimulate the brain and cause seizures or migraines and contribute to Alzheimer’s. MSG contains this neurotransmitter
Endorphin function and example of malfunction
Neurotransmitter that influences the perception of pain and pleasure. imbalance can lead to heightened sensitivity to pain and mood disorders; decreased endorphin levels might contribute to chronic pain or depression
Agonist
Molecule that increases neurotransmitter actions
Antagonist
Molecule that blocks a neurotransmitter action
Somatic nervous system function
enables voluntary control of skeletal muscles
Autonomic nervous system
Controls glands and internal organ muscles. Automatic and can self regulate
Sympathetic nervous system function
Arouses and expends energy. (accelerates heartbeat, dilates pupils, raise blood pressure, etc)
Parasympathetic nervous system function
Calms and conserves energy. (decreases heartrate, contracts pupils, lowers blood pressure, etc)
Nerves
Groupings of axons found in the peripheral nervous system
Reflex
A self-defense mechanism without you being conscious of the action. This happens outside of the CNS
Endocrine system
A slower chemical communication system that encompasses glands that release hormones into the bloodstream
Adrenal glands
A pair of glands that sit above kidneys that secrete hormones (epinephrine or adrenaline, and norepinephrine)
Pituitary gland
Under influence of hypothalamus, this gland controls growth and other endocrine glands
Marcus Raichle Hypothesis
Brain uses 20% of the body’s entire energy budget even when not engaged in any particular task
Vogel and Bogen
first to perform a commissurotomy (creating a split brain)