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What is the first function of the digestive system?
ingestion of nutrients
What is the second function of the digestive system?
secretion
What is the third function of the digestive system?
mechanical and chemical processing
What is the fourth function of the digestive system?
absorption
What is the fifth function of the digestive system?
excretion
What is the ingestion of nutrients?
food and liquids enter the body through the mouth
What begins the digestive process?
ingestion of nutrients
Where does the digestion of food begin?
mouth
What is mechanical processing?
Chewing and muscle contractions break food into smaller pieces; prepares food for easier chemical digestion
What is secretion?
digestive organs release substances into the GI tract
What does secretion include?
enzymes, acids, bile, and mucus
Why is secretion helpful?
breaks down food and protect digestive tissues
What is absorption?
the movement of nutrients from digested food into the blood or lymph
Where does absorption mainly occur?
small intestine
What is the function of absorption?
allows the body to use nutrients for energy, growth, and repair
What is excretion?
undigested material becomes waste
Where does waste move?
large intestine where water is absorbed
What is the mouth?
entry point for food into the digestive tract
What is the purpose of saliva?
begins chemical digestion
What is the esophagus?
muscular tube that connects the mouth to the stomach
Where does peristalsis begin?
esophagus
What is the function of the esophagus?
transports the bolus to the stomach for further digestion
What is the stomach?
muscular organ that stores food temporarily after swallowing
What is the function of the stomach?
churns and mixes food with gastric juices
What begins protein digestion?
acid and enzymes, turn food into chyme
What is the small intestine?
main site for digestion and nutrient absorption
What is the purpose of the small intestine?
enzymes and bile break down food further
Where do nutrients pass in the small intestine?
into blood or lymph for the body to use
What is the main site for mechanical digestion?
stomach
What is the main site for chemical digestion?
small intestine
What is the large intestine?
absorbs water and electrolytes from indigestible food
What does the large intestine form and store?
feces until elimination
What does the large intestine house?
bacteria; aid in breaking down ramaining nutrients
What is the rectum?
stores feces before they are eliminated
What does the rectum signal?
when it’s time to have bowel movement
What ends the digestive tract?
rectum at the anus for excretion
What are the 4 accessory organs?
salivary glands, liver, pancreas, gallbladder
What are accessory organs?
aids digestion but food does not pass through it
What are salivary glands?
produce saliva: water and mucus to lubricate food
What does the salivary gland help form?
bolus for easy swallowing
What do salivary glands support?
oral hygiene; washing away food and bacteria
What is the liver?
produces bile, which emulsifies fats for digestion
What does the liver process?
nutrients from the hepatic portal blood
What organ performs metabolism?
liver
What is the pancreas?
produces digestive enzymes (amylase, lipase, proteases) for the small intestine
What does the pancreas secrete?
bicarbonate to nuetralize stomach acid in the small intestine
What does the pancreas support?
chemical digestion of carbs, proteins, and fats
What is the gallbladder?
stores and concentrate bile produced by the liver
What does the gallbladder release?
bile into the small intestine when fats are present
What is the function of the gallbladder?
emulsifies fats to increase digestion efficiency
What is the first layer of the GI tract (outside-in)?
serosa
What is the second layer of the GI tract (outside-in)?
muscularis
What is the third layer of the GI tract (outside-in)
submucosa
What is the fourth layer of the GI tract (outside-in)?
mucosa
What makes up the serosa?
connective tissue and a layer of epithelial cells
What is the function of the serosa?
outermost layer; protects organs and reduces friction as they move in the abdominal cavity
What is the muscularis made of?
muscle and nervous tissue
What is the function of muscle in the muscularis?
moves and mixes food through peristalsis and segmentation
What is the function of nervous tissue in the muscularis?
coordinates contractions via the myenteric plexus
What is the purpose of the muscularis?
essential for motility and proper digestion
What is the submucosa made up of?
connective, nervous, and lymphatic tissue
What is the function of connective tissue in the submucosa?
supports the mucosa and binds it to the muscularis
What is the purpose of nervous tissue in the submucosa?
regulates secretion and local blood flow
What is the purpose of lymphatic tissue in the submucosa?
helps defend against pathogens in the gut
What is the mucosa made up of?
epithelial, muscle, nervous, and lymphatic tissue
What is the purpose of epithelial tissue is the mucosa?
lines the lumen and absorbs nutrients
What is the purpose of muscle tissue in the mucosa?
creates fold and movement to mix food
What is nervous and lymphatic tissue in mucosa?
coordinate secretion, absorption, and immune defense
Where is the myenteric plexus located?
muscularis externa
What is the myenteric plexus?
major site of nerve control/innervation in the GI tract, mostly parasympathetic
What does the myenteric plexus control?
muscle contractions for peristalsis and segmentation
What is the myenteric plexus essential for?
coordinating motility throughout the digestive tract
What is the muscularis externa?
major site of innervation in GI tract (mostly parasympathetic)
What is the inner circular layer of the muscularis externa?
squeezes the lumen to mix and push food
What is the outer longitudinal layer of the muscularis externa?
shortens the tube to move food along
What does the muscularis externa surround?
lumen; allowing controlled movement based on radius and length
What is the first sub layer of the mucosa (inside-out)
epithelium
What is the second sub layer of the mucosa (inside-out)?
lamina propria (aka gut-associated lymphatic tissue - GALT)
What is the third sublayer of the mucosa (inside-out)?
muscularis mucosae (smooth muscle)
What is the mucosa: epithelium?
top layer of the mucosa, lines the lumen
What is the mucosa:epithelium made up of?
simple/stratified columnar cells
What cells are made in the mucosa:epithelium?
enterocytes, enterendocrine cells, mucin-producing cells
What are enterocytes?
where fat molecules enter through diffusion
What are enteroendocrine cells?
secrete hormones
What are mucin-producing cells?
secrete mucus for protection
What is the lamina propria of the mucosa?
supports small blood vessels and lymph nodes
What is the lamina propria of the mucosa made up of?
connective tissue layer beneath the epithelium
What does the lamina propria of the mucosa provide?
nutrient supply and immune defense
What is the muscularis mucosae of the mucosa?
shapes folds (villi) and microvilli to increase surface area
What is the muscular mucosae of the mucosa made up of?
thin layer of smooth muscle
What does the muscularis mucosae of the mucosa aid in?
movement of mucosa for better absorption and secretion
Where does peristalsis occur?
esophagus, stomach, small intestine, large intestine
What is part of macro motility?
peristalsis and segmentation
What is peristalsis?
wave-like forward contractions of smooth muscle
What is the primary function of peristalsis?
move food forward through the GI tract
What is segmentation?
back-and-forth movements that mix food with digestive juices
Where does segmentation occur?
small intestine
What is the primary function of segmentation?
mixes chyme to enhance digestion and absorption
What is part of micro motility?
phasic and tonic contractions
What are tonic contractions?
sustained, long contractions of smooth muscle