effectors (glycolysis, gluconeogenesis, PDH, TCA)

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17 Terms

1
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hexokinase inhibitor

G6P

2
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hexokinase activator

AMP

3
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PFK inhibitor

ATP/citrate/H+

4
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PFK activator

AMP, F 2,6 BP

5
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pyruvate kinase inhibitor

ATP/alanine

6
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pyruvate kinase activator

F 1,6 BP

7
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pyruvate carboxylase inhibitor

ADP

8
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pyruvate carboxylase activator

acetyl CoA

9
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PEP carboxykinase inhibitor

ADP

10
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F 1,6 BPase inhibitor

F 2,6 BP, AMP

11
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F 1,6 BPase activator

citrate

12
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PDH allosteric inhibitor

ATP, NADH, acetyl CoA

13
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PDH allosteric activator

ADP, pyruvate

14
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PDH covalent modification inhibitor

low glucose

glucagon deactivates E1 to save pyruvate

15
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isocitrate dehydrogenase activator

ADP

16
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isocitrate dehydrogenase inhibitor

ATP, NADH

17
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alpha ketoglutarate dehydrogenase inhibitor

ATP, NADH, succinyl CoA