BIOCHEMISTRY - LIPIDS

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<p>What is the name of this molecule and what category of lipids does it fit into?</p>

What is the name of this molecule and what category of lipids does it fit into?

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1
<p>What is the name of this molecule and what category of lipids does it fit into?</p>

What is the name of this molecule and what category of lipids does it fit into?

triacylglycerol

storage lipids

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2

What is the main function of structural lipids?

support of biological membranes

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3
<p>What is the name, category, and net charge of this lipid?</p>

What is the name, category, and net charge of this lipid?

phosphatidylglycerol

glycerophospholipid

net -1

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4

What does the following carbon skeleton tell you about the structure of the fatty acid?

18:2 (9,12)

common name: linoleic acid

there are 18 carbons with 2 double bonds between carbons 9-10 and 12-13

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5
<p>What is the name of this molecule and what category of lipids does it fit into?</p>

What is the name of this molecule and what category of lipids does it fit into?

glycerophosolipid

phospholipids (structural lipids)

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6
<p>What is the name and category of this lipid?</p>

What is the name and category of this lipid?

glucosylcerebroside

sphingolipid (glycolipid)

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7
<p>What is the name of this molecule and what category of lipids does it fit into?</p>

What is the name of this molecule and what category of lipids does it fit into?

sphingolipid

phospholipids (structural lipids)

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8
<p>What is the name, category, and net charge of this lipid?</p>

What is the name, category, and net charge of this lipid?

phosphatidylethanolamine

glycerophospholipid

net 0

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9

What is the common name of this fatty acid?

20:0

arachidic acid

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10

What type of bond attaches fatty acids in sphingolipids?

amide bond

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11
<p>What is the name and category of this lipid?</p>

What is the name and category of this lipid?

sphingomyelin

sphingolipids (glycolipids)

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12

What is the most decorated biomolecule of all time?

cholesterol

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13
<p>What is the name of this molecule and what category of lipids does it fit into?</p>

What is the name of this molecule and what category of lipids does it fit into?

sphingolipid glycolipids (structural lipids)

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14

What is cholesterol a precursor of?

Vitamin D bile salts hormones

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15
<p>What is the name, category, and net charge of this lipid?</p>

What is the name, category, and net charge of this lipid?

phosphatidylcholine

glycerophospholipid

net 0

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16

What is the common name of this fatty acid?

18:0

stearic acid

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17

What are the main features of cholesterol?

made of 27 carbons has a steroid nucleus amphipathic with polarity at C3 due to an OH group four ring structures: 3 six ring and 1 five ring

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18
<p>What type of fatty acid is this and why?</p>

What type of fatty acid is this and why?

saturated there are no double bonds

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19
<p>What is the name, category, and net charge of this lipid?</p>

What is the name, category, and net charge of this lipid?

phosphatidylinositol 4,5-biphosphate

glycerophospholipid

don't worry about charge for this lipid

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20

What are the sterols called in mammals, plants, and fungi?

cholesterol stigmasterol ergosterol

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21

What is the common name of this fatty acid?

14:0

myristic acid

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22
<p>What is the name, category, and net charge of this lipid?</p>

What is the name, category, and net charge of this lipid?

phosphatidylserine

glycerophospholipid

net -1

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23

What is the general structure of a fatty acid?

polar head group hydrocarbon chain

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24

What are the names of the four phospholipases?

phospholipase A1, A2, C, and D

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25

What configuration of double bonds in unsaturated fatty acids has the highest melting point?

trans-configuration

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26

What is the common name of this fatty acid?

16:0

palmitic acid

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27

What is a phosphodiester bond?

2 ester bonds at different sides of the phosphate

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28
<p>What type of fatty acid is this and why?</p>

What type of fatty acid is this and why?

mono unsaturated there is only one double bond

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29

What type of fatty acids are on carbons 1 and 2 of a glycerophospholipid?

carbon 1: saturated carbon 2: unsaturated

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30

What are the two products of phosphatidylinositol hydrolysis? What do they do?

inositol 1,4,5-triphosphate (IP3) diacylglycerol (DAG)

IP3 triggers the release of intracellular calcium and also aids DAG in the activation of protein kinase C which leads to the regulation of other enzymes through protein phosphorylation

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31

What is a nonessential fatty acid?

our bodies can produce these fatty acids

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32

What is the common name of this fatty acid?

20:4 (5,8,11,14)

arachidonic acid

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33

What three molecules does the metabolism of arachidonic acid produce and what do each of them regulate?

prostaglandin: regulates pain

thromboxane: regulates platelet aggregation

leukotriene: regulates smooth muscles (lungs)

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34

List the following types of fatty acids in order from highest melting point to lowest.

mono unsaturated

saturated

poly unsaturated

saturated > mono unsaturated > poly unsaturated

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35

What is the general structure of a wax?

a long chain fatty acids attached via ester bond to a long chain alcohol

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36

Describe the relationship between solubility and carbon amount in fatty acids.

As the carbon chain increases, the solubility decreases.

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37
<p>What type of fatty acid is this and why?</p>

What type of fatty acid is this and why?

poly unsaturated there is more than one double bond

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38

What is an essential fatty acid? (give an example)

our bodies cannot produce these fatty acids

ex: omega-3 (linolenic acid) 18:3 (9, 12, 15)

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39

What is the common name of this fatty acid?

12:0

lauric acid

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40
<p>What functional group is this?</p>

What functional group is this?

acyl

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41

What is the main biological function of triacylglycerol? What is another function?

fuel storage insulation

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42

How do aspirin and ibuprofen work?

they work by inhibiting the enzyme COX which then decreases the production of thromboxane and prostaglandins

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43

Describe saponification.

triacylglycerol reacted with a base (NaOH or 2KOH) and heated to form glycerol and soap (K+ salts of fatty acids)

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44

Describe the 4 fat-soluble vitamins and their functions.

Vitamin A: aids in increasing vision

Vitamin D: needed for bone formation

Vitamin E: "antioxidants"

Vitamin K: aids in the blood coagulation process

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