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PHARM
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Each drug has at least three names…+ example
Chemical name, generic name, brand(trade) name
Ex:
Chemical name: B-(3, 4 dihydroxyphenyl)-a-methylaminoethanol
Generic name: Epinephrine
Brand (trade) name: Epi-pen
The four things you need to know when giving a medication (+definitions/examples)
1) Indications — helps the patient; indicates you should give it
2) contraindications — when you shouldn’t use it (ex: don’t use albuterol if you don’t hear wheezing or there’s no bronchoconstriction. Just because you can doesn’t mean you should)
3) Side effects: common ones include nausea, headaches, dizziness, tachycardia
4) Untoward effects / adverse effects: allergic reactions, fainting, may cause death; more severe and life threatening to ABCs (vomiting is also included since its a risk to aspiration)
Medication Safety / Clinical Judgement
Administering or assisting with/medication is a serious responsibility, so it’s important to know the medication and use good judgment in administering it. i
Medication authorization is given via…
off-line medical direction (standing orders) or on-line medical direction (speak directly to physician)
The Six Rights
TRAMP-ED!
Right Time
Right Route
Right Amount
Right Medication
Right Patient
(Expired)
Right Documentation (include vitals pre and post)
Routes of administration
-Oral (PO)
-Sublingual (SL)
-Inhaled
-Intramuscular (IM)
-Intranasal (IN) — done via a Mucosal atomization device (MAD)
-Subcutaneous (SubQ)
-Intraosseous (IO)
-Endotracheal (ET)
-Intravenous (IV)
Oral (PO)
Easiest, longest to have effect, must be alert + able to swallow
Sublingual (SL)
Under the tongue; not for chewing. Absorb fast (3-5mins) but IV is faster
Inhaled
Patent airway, must be breathing
Intranasal (IN) — Mucosal Atomization Device (MAD)
MAD helps to deliver meds via this route; absorbs fast. Only need access to nare; don’t need any patient participation
Subcutaneous (SubQ)
Under the skin; EMTs don’t give meds this way
Intraosseous (IO)
Drill into middle of bone and give through bone
Endotracheal (ET)
Liquid and bag it into a tube in throat; not preferred or commonly used
Intravenous (IV)
Into the vein
Pharmacodynamics (PD)
Study of the effects of medications on the body
Pharmacokinetics (PK)
Study of absorption and elimination in the body
Patient-specific factors change how a med is absorbed, works, and is eliminated (medications are usually metabolized in the liver and excreted via the kidneys; peds have higher metabolism and may need a higher dose because of this)
Documentation
-Document assessments and reassessments
-Clearly document medications administered
What medications can EMTs administer
Aspirin, oral glucose, activated charcoal, oxygen, narcan, epipen, albuterol
What medications can EMTs assist with? (MUST HAVE PRESCRIPTION)
Inhaler, nitroglycerin, epipen
Aspirin: Dose
81mg baby chewable aspirin, not adult –3 or 4 of them (324mg) or 1 325mg adult
Chewing is faster; absorbed faster. Adult is swallowed
Aspirin: Route
Chewed/PO
Aspirin: MoA
Prevents further aggregation of platelets (does not ‘bust’ clots)
Aspirin: indications
Cardiac nature chest pain / discomfort (1 drug that we know has tangible benefit to MI patients)
Aspirin: contraindications
Asthma (can induce an attack; however, incidence is low), recent trauma, GI bleeding (causes further bleeding), use in children (may cause Reye’s syndrome; acetaminophen used in children)
Side effects of aspirin
GI upset, N/V, heart burn
Do you need medical command for aspirin
Not required
PA protocol: complete dose or regive whole dose (aspirin)
Regive whole dose (324mg); some states have local protocols where you complete the dose if the patient is already taking aspirin
Oral Glucose Dose
15g (1 single dose tube or 1/3 triple dose tube)
Oral Glucose Route
Buccal (cheek); Park in between gums in mouth; try not to swallow
Oral Glucose MoA
Increases blood sugar level
Oral Glucose Indications
AMS with a history of DM, with suspected hypoglycemia (may need to microdose until you get amount if AMS)
Oral Glucose Contraindications
Unable to follow simple commands, unable to protect airway (put in recovery position to protect airway)
Oral Glucose side-effects
Possible hyperglycemia
Is medical command required for oral glucose
No
Notes about Oral Glucose:
Be sure to protect the airway, It may be possible to give to pt w/severe AMS, low LOC, remember hypoglycemia is a STROKE MIMIC!
ALSO TREAT WHEN BELOW 60mg/dL IN PA!!
Oxygen dose
Given in LPM: NC 4-6LPM, NRB 15LPM
Oxygen route
Inhalation
Oxygen MoA
Provides increased % of O2 in inhaled air (Doesn’t change CO2 / anemia. So it doesn’t necessarily increase SpO2)
Oxygen Indications
Any patient in respiratory distress or suspected shock
Oxygen contraindications
None for ER use
Do you need med command for oxygen
No
Oxygen side effects
Long-term, non-humidified use can cause dehydration and nose bleeds (doesn’t go through nose so its not humidified in the nasal passages)
Activated Charcoal (ActiChar) dose
Adult 25-30g (1-2 bottles)
Pedi 12.5-25g (1.5-1 bottle)
ActiChar is no longer…
A required medicine on an ambulance
Route of ActiChar
Oral (PO)
MoA of ActiChar
Binds to ingested particulate (binds to what’s in stomach to prevent further absorption)
Indications of ActiChar
Ingestion of poison/toxin w/ medical command order***
Contraindications of ActiChar
Unable to protect airway, swallow, or follow simple commands. Ingestion of caustic substance. Exposure to toxin/poison via means other than ingestion
Side effects of ActiChar
Vomiting, black/tar stool, a few days post administration (not designed to make you vomit; prevents further absorption)
Is medical command required for ActiChar?
Must contact PRIOR TO ADMINISTRATION
ActiChar notes
If vomiting occurs, repeat the dose once. Vomiting is not the desired effect, but a very frequent complication. (Often unable to meet dosing guidelines bc most ambulances only carry 1)
“if it burns on way down, it will burn on way up.”
Bronchodilator inhaler/albuterol treatment dose
Inhaler: 1 Rx dose (usually 2 puffs)
Albuterol treatment: 2.5mg (through handheld nebulizer)
Bronch./albut. route
inhalation
Bronch./albut. MoA
Causes bronchodilation, allowing air to more easily pass thru airway structures. Beta 2 agonist (B2 exists on lungs)
Bronch./albut. Indications
Respiratory distress with signs of bronchoconstriction, wheezing
Usually used in asthmatics, COPD, bronchoconstriction pts (only suspect when wheezing or silent lung sounds. sometimes giving albuterol to silent lung sounds can make them become wheezing lung sounds which is an improved condition)
Bronch./albut. contraindications
Broncho-constriction not the suspected cause of respiratory distress
Bronch./albut. side effects
Increased HR (may not want to give to heart pts), anxiety, shaking, nervousness
Bronch./albut. med command
Must call after first adminstration for any subsequent adminstrations
Bronch./albut. notes
You do not need a full set of vitals or assessment; the albuterol treatment that is given in a nebulizer is an administered medication
Nitroglycerin (Nitro) dose
0.4mg (equal to 1 spray or tablet)
Nitro route
SL
Nitro MoA
Dilates coronary arteries, reducing workload of heart, thereby reducing O2 demand (limits ischemia and damage done by MI)
Nitro indications
Pts having chest pain as suspected to cardiac issues
DOES NOT CHANGE OUTCOMES!!! Only helps with pain
Nitro contraindications
Non cardiac CP, ED drug use in last 24-48 hours (or pulmonary hypertension drugs), systolic BP less than 100, recent dosing
Nitro side effects
light headedness, fainting, drop in BP, anxiety, increased HR
Nitro Med Command
Must call after 1st adminstration for any more
Nitro Notes
Must ask all patients about ED drugs, not just males (females can take ED drugs for pulmonary hypertension), must be careful handling drug bc it can be absorbed into skin and cause headaches, N/V, etc…
Naloxone (Narcan) Dose
2mg
2g/nare
Narcan Route
Intranasal
Narcan MoA
Reverses the effects of narcotics, including depressed level of consciousness and respiratory depression
Narcan Indications
Suspected narcotic overdose; coma of an unknown cause
Narcan contraindications
Pt breathing adequately and able to maintain own airway
Narcan Side effects
May preciptate withdrawl in pts dependent on narcotics
Narcan med command
Not required
Narcan Notes
-Only used to attain adequate respiratory effect
-Helpful but still manage ventilation. Use a BVM if needed until pt can breathe on own.
Epinephrine Auto-Injectors Dose
0.3mg for adults, 0.15mg for pedi
Epinephrine Auto-Injectors route
IM
Epinephrine Auto-Injectors MoA
Sympathetic activation, bronchodilation, vasoconstriction
Epinephrine Auto-Injectors indications
Severe allergic rxn w/ signs of AMS or respiratory compromise
Epinephrine Auto-Injectors contraindications
Mild allergic rxn
None in true emergency setting
Epinephrine Auto-Injectors side effects
increase HR, anxiety, shaking, nervousness, headache, numbness in extremities
Epinephrine Auto-Injectors Med Command
Must call after first administration for additional ones
Epinephrine Auto-Injectors Notes
You do not need a full set of vital signs or assessment
Medication Education
Do pts know how to take meds (Show me how you take this…)
85+ meds interact poorly w/ grapefruit
antibiotics and birth control
NSAIDs can reduce effectiveness of antihypertensives
Common med: Metformin
antihyperglycemic — reduces hyperglycemia
Common med: HCTZ
Water Pill, decreases blood pressure
Common med: Lisinopril / amlodipine
BP meds
Common med: omeprazol
GERD
Common med: Simvastatin
High cholesterol
Ways fluids and medications may be adminstered into the vein
Saline lock, Drip set
Saline Lock
-Catheter placed into vein
-Cap (Lock) placed over end of catheter
-Lock contains port for administering meds
Drip Set
-Clear plastic tubing connecting fluid bag to needle or catheter
-3 parts: drip chamber, flow regulator, drug/needle port
-Extension set makes it easier to carry/disrobe pt w/o pulling out IV
What to do before setting up IV fluid
-Inspect IV bag to be sure it contains the solution that was ordered
-Ensure it is clear, did not leak, is not expired
What to do while setting up IV fluid
-Remove protective coverings from the port of the fluid bag and the spiked end of the tubing
-Insert spiked end of tubing into fluid bag
-Close flow regulator
-Fill the drip chamber
-Open the flow regulator
-Set appropriate rate
Maintaining an IV
-Troubleshoot flow problems: constricting bands left in place by mistake, flow regulator left closed, clamp closed on tubing, tubing kinked, tubing caught under pt or equipment.
-Monitor IV sites for infiltration