Saliva

Saliva

It is an important substance for the proper digestion of food, and it also plays a key role as a natural anticaries agent.

Whole Saliva

Mainly the mixture of secretion of salivary glands.

Slightly Acidic

Is saliva slighty acidic or slightly basic?

1-1.5 L

How many volumes of saliva do adults produce a day?

No

Is saliva produced a lot during sleep?

Parotid - Submandibular - Sublingual

What are the 3 major salivary glands?

Serous

What type of gland does the parotid gland secrete?

Serous

What type of gland does the von ebner gland secrete?

Mucous

What type of gland does palatine and glossopalatine glands secrete?

Mixed (Chiefly Mucous)

What type of gland does the glands of blandin and nuhn secrete?

Mixed (Predominantly Mucous)

What type of gland does the sublingual gland secrete?

Mixed (Predominantly Serous)

What type of gland does the submandibular gland secrete?

Water

The saliva is composed of 99% of what substance?

Solutes

The saliva is composed of 1% of what substance?

Proteins

Organic substance found in saliva that includes alpha amylase, maltase, lingual lipase, agglutinin, other polypeptides.

Immuno-globulins

Organic substance found in saliva for immunity.

Non-Immunologic Protein

Organic substance found in saliva that are antibacterial proteins.

Salivary Amylase

Most important component of saliva.

Salivary Amylase

Starts the digestion of starch in the mouth.

Von Ebner’s Gland

Salivary lipase is secreted by?

Salivary Lipase

Protein that helps in the digestion of fats.

Maltase

Protein that helps in converting maltose to glucose.

Immuno-Globulin

Protein that helps in reducing bacterial growth; essential for bacterial metabolism and inhibits bacterial colonization.

Lysozymes

Protein that is antibacterial and acts on s. mutans.

Lactoferrin

Protein that acts as bacteriostatic; reduces the mouth of free iron in the blood, required for metabolism.

Peroxidase (Sailo-Peroxidase)

Protein that inhibits growth and acid production of microorganism.

Glyco-proteins (Mucin)

Protein that acts as lubricant; acts as a protective barrier against excessive wear.

Yes

Does glyco-proteins (mucin) have antibacterial properties?

Histatins

Most common types: histatin 1, 3, and 5; has antimicrobial properties.

Agglutinin

Protein that has sticky property; helps in clumping of bacteria which can be easily flushed away by saliva and swallowing.

Statherin and Protein Rich Proteins

Proteins that prevents formation of dental calculus; inhibits precipitation of calcium phosphate salts.

Statherin and Protein Rich Proteins

Proteins that help in the formation of hydroxyapatite crystals in the tooth surface.

Cystatins

Protein that helps in the hydroxyapatite crystal equilibrium which prevents acquired enamel pellicle.

Cystatins

Protein that has protein inhibiting properties and controls proteolytic activity.

Salivary Phosphoprotein

A small acidic _______ ______________ that functions as an inhibitor of spontaneous precipitation of calcium phosphate salts to maintain a stable supersaturated state of saliva.

Statherin

Protein that is found to be a major contributor to the acquired enamel pellicle; may function in the transport of calcium and phosphate during secretion in the salivary glands.

Statherin

In saturated solutions of calcium phosphate minerals, _________ inhibits spontaneous precipitation and crystal growth, providing a protective and reparative but stable environment for the teeth.

Statherin

Acting together with the protein-rich and mucinous proteins, ________ maintains the supersaturated  state of saliva with respect to most calcium phosphate salts in the AEP.

Bicarbonate/Carbonic Acid

Inorganic compound that is the main buffering ion of saliva.

Yes

Is thiocyanate antibacterial?

Sodium - Phosphate - Bicarbonate

These substances help in osmolarity (3).

Calcium - Phosphate

Inorganic substances that are soluble and complexes with carbonate lactate, it binds to protein (2).

Bicarbonate/Carbonic Acid

Most important buffering system; occurs at pH 6.3.

pH 7.2

What is the buffering range of phosphate?

Protein Buffer

Mainly takes place in buffering below pH 5.

Yes

Can large volumes of saliva dilute and buffer biofilm acids?

Statherin

Proline rich-peptide, stabilizes the calcium and phosphate ions.