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Flashcards covering key biology vocabulary and concepts related to DNA, transcription, translation, and gene regulation.
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isotopes
Different forms of the same element.
protons
Two different isotopes of a given element have the SAME number of protons.
neutrons
Two different isotopes of a given element have a DIFFERENT number of neutrons in its nucleus.
unstable
Having different numbers of neutrons makes an atomic nucleus unstable.
radioactive decay
The process by which an unstable atomic nucleus loses energy by emitting ionizing particles or radiation.
griffith
Demonstrations of bacterial transformation was discovered by Griffith.
Avery, McCarty, and MacLeod
The transforming factor is separable according to Avery, McCarty, and MacLeod.
Hershey and Chase
The transforming factor is DNA, discovered by Hershey and Chase.
chargaff
Chargaff discovered ratios of DNA within and between species.
Watson and Crick
Watson and Crick provided the description of the 3D DNA structure.
franklin
Franklin produced an X-ray crystallography of DNA.
Chargaff's rules
Chargaff's rules state that in any species there is an equal number of A and T bases, and an equal number of G and C bases.
meselson and stahl
Semi-conservative replication was demonstrated by Meselson and Stahl.
topoisomerase
Topoisomerase relieves the strain of twisting caused by unwinding during replication.
primase
Primase makes a primer - a short RNA starting point - for synthesis of a DNA strand.
polymerase
Polymerase polymerizes a new strand of DNA by adding nucleotides.
ligase
Ligase ligates or joins together nucleic acids.
origins of replication
Replication begins at special sites called origins of replication.
single-strand binding
Single-strand binding protein binds to and stabilizes single-stranded DNA.
nucleotide triphosphate
Each nucleotide that is added to a growing DNA strand is a nucleoside triphosphate.
deoxyribose
dATP has deoxyribose sugars.
ribose
ATP has ribose sugars.
antiparallel
The antiparallel structure of the double helix affects replication.
transcription
Synthesis of RNA under the direction of DNA.
translation
Synthesis of a polypeptide which occurs under the direction of mRNA.
nuclear envelope
In a eukaryotic cell, the nuclear envelope separates transcription from translation.
mRNA
Eukaryotic RNA transcripts are modified through RNA processing to yield finished mRNA.
genetic information
The central dogma is represented as DNA -> RNA -> protein.
codons
During translation, the mRNA base triplets called codons are read in the 5' to 3' direction.
uracil
In RNA, uracil substitutes for thymine.
promoter
The DNA sequence where RNA polymerase attaches is called the promoter.
terminator
In bacteria, the sequence signaling the end of transcription is called the terminator.
transcription factors
Proteins that assist RNA polymerase in initiating transcription.
activator
An activator is a protein that binds to an enhancer and stimulates transcription.
repressor
The repressor is the product of a separate regulatory gene that inhibits transcription.