IMMUNOSEROLOGY (history)

Discovered SERUM ANTITOXINS that neutralize toxins

Emil Von Behring (1901)

Cellular immunity in tuberculosis

Heinrich Hermann Robert Koch (1905)

Known for his Phagocytic theory of immunity

Elie Metchnikoff (1908)

Known for his contribution to the diptheria antitoxin

Paul Ehrlich (1908)

Discovered the first effective treatment for syphilis

Paul Ehrlich

Invented the word "Anaphylaxis"

Charles Richet (1913)

Responsible for developing Complement fixation tests

Jules Bordet (1919)

Discovered human blood group antigens

Karl Landsteiner (1930)

Demonstrated acquired immunologic tolerance

Frank Macfarlane Burnet (1960)

Theory of acquired Immunological tolerance that paved way for successful ORGAN and TISSUE transplantation

Peter Madawar (1960)

Structure of Antibody research

Gerald Maurice Edelman (1972)

Determining the chemical structure of Antibodies

Rodney Robert Porter (1972)

RIA technique

Rosalyn Sussman Yallow (1977)

Discovery of HLA complex in humans analogous to the H-2 complex in mice

George Davis Snell

Showed that tissue transplants were much more likely to be successful when both donor and recipient shared the same HLA group

Jean Dusset

Discovery of MHC genes which encode cell surface protein molecules important for the immune system's distinction between self and non-self

Baruj Benacerraf

Immunoregulation and the discovery of the principle for production of Monoclonal Antibodies

Niels Kaj Jerne

Worked on a technique to produce Monoclonal bodies

George JF Kohler

Hybridoma technique/Monoclonal Antibodies

Cesar Milstein

Discovered the genetic mechanism that produces Antibody Diversity

Susumu Tonegawa

Development of Cell and Organ Transplantation. Bone Marrow transplantation as treatment of leukemia

Edward Donall Thomas