Chapter 22: Developmental Genetics and Immunogenetics

Totipotent cell

Cell with the potential to develop into any cell type

Determination

Cell committed to a particular cell fate

Irreversibly committed to fate

Specification

Sent for certain fate, but can be changed

Differentiation

Functionally specialized as stable, final identity

Multipatent

Can produce multiple cell types, but not a wide range

Gray Crescent

Prepares dorsal-ventral-axis & region called______

Spemann’s Organizer

A signaling center that “talks” with other tissues to direct development

Induction

When 1 tissue sends signals to change the development of another

Zygote

Fertilized Egg

Blastula

Hollow ball of cells

Gastrula

Cell move toward interior

Speman-Mangold Organizer

Cells of Dorsal blastopore lip are called the ________

Homeotic Gene

Master regulatory genes that direct development of body structures

Hox Genes

Homeotic gene that encodes transcription factors

Apoptosis

programmed cell death

Cells shrink, DNA & organelles get chopped into small pieces

Release signal to attract phagocytic

Necrosis

Messy version of cell death

Cells swells, releases inner contents, causes inflammation