sarcomere proteins

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13 Terms

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Cap-Z

Stabilizes actin

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Leiomodin, tropomodulin, and nebulin

Regulate actin length

3
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Alpha actinin

Comprises z line and provides sarcomere stability

4
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Desmin IF

Anchors z line and provides sarcomere stability

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Vimentin

Gives structural support, regeneration of muscle and hypertrophy

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Dystrophin

Mechanical stability

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Syntrophin

Anchors signaling molecules (nNos)

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Dystroglycan

Structural stability

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Sarcoglycan

Stabilizes cell membrane or sarcolemma

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Integrin

Mechanosensor, important for hypertrophy

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essential light chain

Stabilizes myosin heavy chain neck, allows for more force production

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Regulatory light chain

Modulates contraction kinetics and the lever arms motion

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FAK

Translates mechanical signals into biochemical signals