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what is hemostasis?
stopping the fatal leakage of blood
What are thrombocytes?
platelets, which are small fragments of megakaryocytes
Whata re the 3 steps of Hemostasis?
vascular spasms
platelet plug
coagulation
what happens during vascular spasms?
smooth walls of the blood vessel contract to try and minimize as much blood loss as possible
What happens during platelet plug?
platelets stick to the injured wall of the blood vessel and to each other to block the injury
What happens during coagulation?
clotting happens, due to fibrinogen converting into fibrin which helps sticks the platelets together
How does fibrinogen convert into fibrin?
with Ca2+ present, factor X combines with factor III and produces the enzyme prothrombin, prothrombin converts into thrombin (plasma protein) and thrombin converts fibrinogen into fibrin
what are tthe two different kinds of ways to coagulation?
intrinsic and extrinsic pathway
what happens during the intrinsic pathway?
uses clotting factors within the blood to clot
what happens during the extrinsic pathway?
initiated by clotting factors that are released by nearby damaged tissues or blood vessels
What is Fibrinolysis?
dissolution of a clot
What dissolves a clot?
plasmin
blank helps prevent inappropriate clotting, and one main one it secretes is heparin.
anticoagulants