Antibiotic Sensitivity Testing

any chemical/physical agent synthesized and secreted by some bacteria and fungi that inhibits or kills the growth of other microorganisms

antibiotics

antibiotics are those that are produced by in vitro chemical modifications of natural antibiotics

semi-synthetic

the interaction or cooperation of two or more organizations, substances, or other agents to produce a combined effect greater than the sum of their separate effects

syngergism

the reaction of two drugs produces a combined effect that is not greater than the sum of their separately measured individual effects

additive

This tests bacterial sensitivity to antibiotics by measuring zones of inhibition around antibiotic disks

kirby bauer

What is the purpose of synergism testing

To see if two antibiotics combined are more effective at killing or stopping bacteria than either one alone

the lowest concentration of an antibiotics that inhibits the growth of a test organism

MIC

What does MIC stand for

minimal inhbitory concentration

Portion of the penicillin molceule and render the antibiotic inactive

B-lactam ring

how does the MIC test appear for a resistant organism

cloudy broth in tube