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Eukaryotic Cell
A cell with a nucleus and organelles, including animal and plant cells.
Nucleus
The membrane-bound organelle that houses DNA and controls cellular activities.
Cytoplasm
The gel-like substance within a cell where metabolic processes occur, containing cytosol and organelles.
Cytosol
The aqueous component of cytoplasm, providing a medium for molecular suspension.
Organelles
Specialized structures within a cell, such as the endoplasmic reticulum and mitochondria, that perform specific functions.
Topological Equivalence
A relationship between spaces or membranes that allows for continuity and similarity, facilitating protein movement.
Nuclear Pore Complex (NPC)
Protein-lined channels that regulate the transport of molecules between the nucleus and the cytoplasm.
Sorting Signals
Specific sequences within proteins that direct their movement to the correct cellular compartment.
Translocators
Proteins that facilitate the transport of unfolded proteins across membranes into organelles.
Signal Peptide Sequences
Short sequences within a protein that direct it to its proper location within the cell.
Signal Patches
Three-dimensional arrangements of amino acids crucial for protein sorting, not removed after function.
Mitochondria
Double-membraned organelles responsible for ATP production and cellular respiration.
Endoplasmic Reticulum (ER)
A membranous network involved in protein and lipid synthesis, further divided into rough and smooth ER.
Chaperone Proteins
Proteins that assist in the proper folding of other proteins post-translocation.
Golgi Apparatus
Organelles that modify, package, and distribute proteins and lipids received from the ER.
Actin Filaments
Cytoskeletal components that provide structural support and are involved in cell movement.
Apoptosis
A programmed cell death mechanism that removes unnecessary or damaged cells in a controlled manner.
Caspases
Proteolytic enzymes that drive the processes of apoptosis by cleaving specific proteins.
Stem Cells
Undifferentiated cells capable of self-renewal and differentiation into various specialized cell types.
Gap Junctions
Intercellular connections that allow for direct communication between adjacent cells.
Cadherins
Calcium-dependent cell adhesion proteins that connect cells to each other.
Integrins
Transmembrane proteins that mediate the attachment between cells and the extracellular matrix.