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Flashcards covering key vocabulary and concepts from the histology lecture notes.
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Histology
The study of tissues, requiring microscopic examination of multiple cells.
Four Tissue Classes
Epithelium, Connective, Muscular, and Nervous tissue.
Organ
Composed of two or more tissues functioning together.
Epithelium Tissue Function
Covers body surfaces, lines internal organs/passageways; forms barriers, glands (secrete), surfaces for absorption.
Connective Tissue Function
Support, connect, protect organs; matrix is more abundant than cells; examples include cartilage, bone, tendons, ligaments, blood.
Nervous Tissue Function
Excitable cells that carry signals to and from the central nervous system (brain and spinal cord).
Muscle Tissue Function
Allows for movement; excitable cells responding to stimuli; types: skeletal, cardiac, smooth.
Tissue
Group of similar cells and their cell products.
Matrix
Extracellular space consisting of fibrous proteins and ground substance (goo).
Embryonic Tissue Layers
Ectoderm, endoderm, and mesoderm.
Ectoderm
Outermost layer that develops into epidermis and nervous system.
Endoderm
Inner lining that forms mucous membranes lining the gastrointestinal and respiratory tracts, and digestive glands.
Mesoderm
Middle layer that forms mesenchyme, including muscle, bone, and blood.
Apical Surface
The top of the cells, exposed to the outside or lining an internal passageway/organ.
Basement Membrane
Layer of collagen and adhesive proteins to which epithelial cells adhere.
Simple Epithelium
Single layer of cells named by cell shape (squamous, cuboidal, columnar).
Stratified Epithelium
More than one layer of cells, named by the shape of the cells at the top layer.
Simple Squamous Epithelium
Single layer of flattened cells allowing for easy diffusion (e.g., alveoli of lungs, kidney filters).
Simple Cuboidal Epithelium
Single layer of cube-shaped cells for absorption and secretion (e.g., glands, kidney tubules).
Simple Columnar Epithelium
Single row of tall cells, often with goblet cells (mucus) and microvilli, for absorption and mucus secretion (e.g., lining of stomach and intestines).
Pseudostratified Columnar Epithelium
Looks stratified but all cells contact the basement membrane; contains goblet cells and cilia; traps particles (e.g., respiratory epithelium).
Stratified Squamous Epithelium
Multiple cell layers, named for squamous surface cells; can be keratinized (dead cell layer) or nonkeratinized (live cells all the way up); abrasion resistant (e.g., epidermis, oral mucosa).
Transitional Epithelium
Stratified epithelium named for its function to stretch/expand and recoil (e.g., lining of the bladder).
Fibroblast
Connective tissue cell that produces collagen.
Collagen
Essential component of connective tissues, providing strength and resilience.
Adipocytes
Fat cells that store triglycerides.
Loose Connective Tissue
More ground substance and cells than fibers.
Dense Connective Tissue
More fibers than cells and ground substance.
Areolar Tissue
Loose connective tissue with all three fiber types (collagen, elastic, reticular) and various cell types; acts as packing material everywhere.
Reticular Tissue
Loose connective tissue with heavy reticular fibers; acts as a scaffold for blood-filled organs (e.g., spleen, lymph nodes).
Adipose Tissue
Loose connective tissue for fat storage, cushion, and heat production; filled with adipocytes.
Dense Regular Connective Tissue
Collagen fibers aligned in parallel bundles (tendons, ligaments).
Dense Irregular Connective Tissue
Collagen fibers orientated in random directions (underlying layers of skin).
Chondroblasts
Cartilage cells that produce the rubbery matrix.
Chondrocytes
Mature cartilage cells trapped in the matrix.
Hyaline Cartilage
Basic form of cartilage; in movable joints and fetal skeleton.
Elastic Cartilage
Hyaline cartilage with elastic fibers; highly flexible (external ear, epiglottis).
Fibrocartilage
Hyaline cartilage with abundant collagen fibers; strong (pubic symphysis, intervertebral discs).
Osteon
Structural unit of bone with a central canal for blood vessels and nerves.
Erythrocytes
Red blood cells that carry gases.
Leukocytes
White blood cells that protect the immune system.
Thrombocytes
Platelets that function in blood clotting
Neuron
Nervous tissue cells that transmit information throughout the body.
Glial cells
Nervous tissue cells that Support the function of the neuron.
Skeletal Muscle
Striated, voluntary muscle fibers with multiple nuclei.
Cardiac Muscle
Striated, involuntary muscle fibers with one nucleus and intercalated discs.
Smooth Muscle
Nonstriated, involuntary muscle fibers with one nucleus; found in internal organs.
Tight Junctions
Zipper-like junctions preventing passage between cells (GI and urinary tracts).
Desmosomes
Snap-like junctions holding cells physically together (cervix, heart, skin).
Gap Junctions
Pores allowing transport of signaling molecules and ions between cells (embryonic development, cardiac and smooth muscle).
Exocrine Glands
Connect to the surface with a duct (sweat, oil, mammary, digestive glands).
Endocrine Glands
Secrete hormones directly into the blood; doesn't connect to the surface with a duct.
Hyperplasia
Tissue growth due to increase in cell number (childhood growth).
Hypertrophy
Tissue growth due to enlargement of preexisting cells (body building).
Neoplasia
Abnormal tissue growth forming a mass or tumor.
Atrophy
Shrinkage due to loss of cell size or number.
Necrosis
Pathological cell death due to toxins, trauma, or infection.
Apoptosis
Programmed (healthy) cell death.