Block 1 Pharmacology
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28 Terms
Atropine Class
- Antimuscarinic
Atropine Indications
- bradycardia
- eye conditions
- poisoning by muscarinic agents
Atropine Mechanism
- blocks effects of acetylcholine at Muscarinic M1-M5 receptors of parasympathetic nervous system
Antimuscarinics Contraindications
- angle closure glaucoma
- intestinal atony
- GI obstruction
- Paralytic ileus
- Pyloric stenosis
Antimuscarinics Side Effects
- constipation
- abdominal distension
- dizziness
- nausea/vomiting
- palpitations
- tachycardia
- headache
Digoxin Class
- cardiac glycoside
Digoxin Indications
- atrial fibrillation
- heart failure
Digoxin Mechanism
- inhibits Na-K ATPase, increasing contractile force of left ventricle
Digoxin Contraindications
- constrictive pericarditis
- hypertrophic cardiomyopathy
- myocarditis
- intermittent complete heart block
- 2nd degree AV Block
Digoxin Side Effects
- arrythmias
- nausea/diarrhea/vomiting
- cardiac conduction disorder
- dizziness
- vision disorders
Fluconazole Class
- triazole antifungal
Fluconazole Indications
- Candidal balanitis
- vaginal candidiasis
- cryptococcal meningitis
- tinea pedis (athlete's foot)
- oesophageal candidiasis
- candidiasis
Fluconazole Mechanism
- inhibits fungal cytochrome P450 preventing cell wall synthesis
Fluconazole Contraindications
- acute porphyria
Fluconazole Side Effects
- diarrhoea/vomiting/nausea
- GI discomfort
- headache
Paracetamol Class
- analgesic
Paracetamol Indications
- mild to moderate pain
- pyrexia
- acute migraine
Paracetamol Mechanism
- Inhibits CNS prostglandin synthesis
Paracetamol Side Effects
- anorectal erythema
Rivastigmine Class
- anticholinesterase
Rivastigmine Indications
- mild to moderate dementia
Rivastigmine Mechanism
Reversible, non competitive inhibitor of AChE
Anticholinesterase Contraindications
- intestinal obstruction
- urinary obstruction
Rivastigmine Side Effects
- anxiety
- decreased appetite
- arrythmias
- nausea/vomiting/diarrhoea
- GI discomfort
- hypertension
- UTI
- weight loss
Pyridostigmine Class
- anticholinesterase
Pyriodistigmine Indications
- Myasthenia Gravis
Pyriodistigmine Side Effects
- abdominal cramps
- diarrhoea/nausea/vomiting
- excessive tearing
- hypersalivation
Pyriodistigmine Mechanism
- reversibly, copetitively inhibits AChE at NMJ
Note 
Flashcards (45)