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Primary functions of the respiratory system
Gas exchange, gas conditioning, sound production, olfaction, and defense.
Two cyclic phases of respiration
Inspiration (oxygen-rich air enters the lungs) and expiration (oxygen-poor air leaves the lungs).
External respiration
The exchange of gases between the air in the lungs and the blood in pulmonary capillaries.
Internal respiration
The exchange of gases between blood in systemic capillaries and body tissues.
Gas conditioning
It warms, humidifies, and cleanses air to prevent lung damage.
Location of gas conditioning
In the nasal cavity and paranasal sinuses.
Defense against pathogens in the respiratory system
Mucus, cilia, immune cells, and nasal hairs trap and remove pathogens.
Role of cilia in the respiratory tract
They beat in a coordinated motion to move mucus and trapped particles out of the airways.
Conducting portion of the respiratory system
Nose, nasal cavity, paranasal sinuses, pharynx, larynx, trachea, bronchi, and terminal bronchioles.
Respiratory portion of the respiratory system
Respiratory bronchioles, alveolar ducts, alveolar sacs, and alveoli.
Four paranasal sinuses
Frontal, maxillary, ethmoid, and sphenoid sinuses.
Function of the paranasal sinuses
They lighten the skull, aid in gas conditioning, and serve as resonance chambers for speech.
Epithelium lining most of the nasal cavity
Pseudostratified ciliated columnar epithelium.
Contribution of nasal conchae to respiration
They create turbulence, increasing air contact with the mucosa for better conditioning.
Function of goblet cells in the nasal cavity
They secrete mucus that traps debris and humidifies incoming air.
Role of the nasal septum
It divides the nasal cavity into left and right halves.
Structure connecting the nasal cavity to the pharynx
The choanae.
Function of olfactory epithelium
It contains olfactory receptor neurons responsible for detecting airborne molecules and transmitting smell signals.
Boundaries of the nasal cavity
Roof (ethmoid bone), floor (hard palate), medial wall (nasal septum), and lateral wall (nasal conchae).
Function of nasal hairs (vibrissae)
They trap large particles and debris before air enters the respiratory tract.
Three regions of the pharynx
Nasopharynx, oropharynx, and laryngopharynx.
Epithelium lining the nasopharynx
Pseudostratified ciliated columnar epithelium for air filtration.
Epithelium lining the oropharynx and laryngopharynx
Stratified squamous epithelium for protection during swallowing.
Primary function of the epiglottis
To prevent food from entering the trachea during swallowing.
Three major cartilages of the larynx
Epiglottis, thyroid cartilage, and cricoid cartilage.
Contribution of the thyroid cartilage to voice production
It provides attachment for vocal cords.
Function of the true vocal cords
They vibrate to produce sound.
Function of the false vocal cords
They protect the true vocal cords and help close the larynx during swallowing.
Effect of changing tension on the vocal cords
Increased tension produces a higher pitch, while decreased tension produces a lower pitch.
Structure connecting the pharynx to the trachea
The larynx.
Shape of tracheal cartilages
C-shaped instead of complete rings to provide structural support while allowing flexibility for swallowing.
Epithelium lining the trachea
Pseudostratified ciliated columnar epithelium.
Pseudostratified ciliated columnar epithelium
Lines the trachea.
Carina
Marks the bifurcation of the trachea into the primary bronchi and triggers the cough reflex.
Primary bronchi
The right bronchus is wider, shorter, and more vertical, making it more likely for foreign objects to enter.
Levels of bronchi
Primary, secondary (lobar), and tertiary (segmental) bronchi.
Terminal bronchioles
The last part of the conducting zone.
Respiratory bronchioles
The first part of the respiratory zone.
Alveolar ducts
They transport air to alveolar sacs where gas exchange occurs.
Simple squamous epithelium
Lines alveoli.
Surfactant
Reduces surface tension, preventing alveolar collapse.
Pulmonary capillaries
Surround alveoli and facilitate the diffusion of oxygen into the blood and carbon dioxide out of the blood.
Right lung lobes
Three (superior, middle, and inferior).
Left lung lobes
Two (superior and inferior).
Cardiac notch
An indentation in the left lung that accommodates the heart.
Pleural membrane
Secretes pleural fluid to reduce friction and allow smooth lung expansion.
Layers of the pleura
The visceral pleura (covers the lung surface) and parietal pleura (lines the thoracic cavity).
Pleural cavity
The space between the visceral and parietal pleura containing pleural fluid.
Diaphragm
Contracts to increase thoracic volume, causing inspiration.
Diaphragm during exhalation
Relaxes, reducing thoracic volume and causing expiration.
Lung surfaces
Costal (contacts ribs), mediastinal (contacts the heart and major vessels), and diaphragmatic (rests on the diaphragm).
Hilum of the lung
The entry and exit point for blood vessels, bronchi, and lymphatics.
Alimentary canal
Digestive tract.
Structures of the alimentary canal
Mouth, pharynx, esophagus, stomach, small intestine, large intestine, and anus.
Accessory digestive organs
Tongue, teeth, salivary glands, liver, gallbladder, and pancreas.
Histological layers of the digestive tract
Mucosa, submucosa, muscularis externa, and serosa/adventitia.
Esophagus epithelium
Stratified squamous epithelium for protection against friction.
Stomach epithelium
Simple columnar epithelium with mucus-secreting cells for acid protection.
Function of the submucosa
Contains blood vessels, lymphatics, glands, and nerve plexuses that support digestion.
Muscularis externa
Has circular and longitudinal smooth muscle layers for peristalsis.
Difference between serosa and adventitia
Serosa is a slippery serous membrane covering organs, while adventitia is loose connective tissue anchoring organs.
Function of the enteric nervous system
Controls gut motility, secretion, and local reflexes independent of the central nervous system.
Regions of the oral cavity
The vestibule (space between cheeks/lips and teeth/gums) and the oral cavity proper.
Hard palate
It is made of bone.
Soft palate
It is muscular and ends in the uvula.
Major salivary glands
Parotid, submandibular, and sublingual glands.
Parotid gland secretion
Serous fluid with digestive enzymes.
Submandibular gland secretion
Mixed serous and mucous secretions.
Sublingual gland secretion
Mostly mucous secretions for lubrication.
Intrinsic muscles of the tongue
They change the shape of the tongue.
Extrinsic muscles of the tongue
They move the tongue during chewing and speech.
Lingual frenulum
It anchors the tongue to the floor of the mouth.
Types of papillae on the tongue
Filiform, fungiform, circumvallate, and foliate.
Human teeth sets
Deciduous (baby) teeth have 20, and permanent teeth have 32.
Dental formula for deciduous teeth
2 incisors, 1 canine, and 2 molars per quadrant.
Dental formula for permanent teeth
2 incisors, 1 canine, 2 premolars, and 3 molars per quadrant.
Types of tonsils
Palatine, pharyngeal (adenoids), and lingual tonsils.
Function of the tonsils
They act as immune defense structures in the pharynx.
Tonsils removed during tonsillectomy
Palatine tonsils.
Role of enamel in teeth
It is the hardest substance in the body, protecting the tooth surface.
Function of dentin
It provides structural support beneath enamel.
Cementum contribution to tooth function
It anchors the tooth to the periodontal ligament.
Pulp cavity
It is the innermost part of the tooth containing nerves and blood vessels.
Function of the esophagus
It transports food from the pharynx to the stomach via peristalsis.
Function of the lower esophageal sphincter
It prevents stomach acid from refluxing into the esophagus.
Regions of the stomach
Fundus, body, and antrum.
Function of rugae in the stomach
They allow the stomach to expand after eating.
Layers of the stomach's muscularis externa
Outer longitudinal, middle circular, and inner oblique.
Role of gastric glands
They secrete digestive enzymes and acids.
Parietal cells secretion
Hydrochloric acid (HCl) for digestion and intrinsic factor for vitamin B12 absorption.
Chief cells secretion
Pepsinogen, which is activated to pepsin for protein digestion.
Mucus-secreting cells in the stomach
They produce a protective mucus layer to prevent acid damage.
Role of the pyloric sphincter
It regulates the passage of chyme from the stomach to the small intestine.
Sections of the small intestine
Duodenum, jejunum, and ileum.
Structures increasing surface area for absorption in the small intestine
Villi, microvilli, and plicae circulares.
Peyer's patches
They are lymphoid tissue aggregates in the ileum that protect against pathogens.
Intestinal glands (crypts of Lieberkühn)
They secrete digestive enzymes and mucus.
Function of the large intestine
Water absorption, fecal formation, and gut microbiome activity.
Sections of the colon
Ascending, transverse, descending, and sigmoid colon.
Function of the rectum
It stores fecal matter before defecation.