IBD/IBS Blackboard Quiz

Which of the following drugs has a warning regarding the development of suicidal ideation?

Tegaserod

Which of the following drugs can only be prescribed to patients who have a gallbladder?

Eluxadoline

Which one of the following would be LEAST appropriate to use for the maintenance of remission for ulcerative colitis?

Prednisone

Of all the medications the patient is taking, which is mostly likely to worsen her IBS?

Diphenhydramine

Given the patient's reported bloating and flatulence, which approach listed below would be MOST appropriate for the pharmacist to recommend?

Reduce intake of fermentable foods

All of the following are typical complications of Crohn's disease EXCEPT

Hypothyroidism

Which drug is a biologic that inactivates integrin molecules on T lymphocytes?

Vedolizumab

Which drug is a prodrug dimer of two 5 aminosalicylic acids that is cleaved in the colon by bacterial enzymes?

Olsalazine

The patient expresses that his current bowel habits require significant straining. Adding which medication below would be MOST appropriate to address this concern?

Linaclotide

Which of the following drugs has a mechanism of action most similar to that of loperamide?

Eluxadoline

Which of the following drugs would be MOST appropriately considered for this patient to help relieve her IBS symptoms?

Amitriptyline

Which of the following IBD treatments is only used as a subcutaneous injection?

Humira

Which of the following would be the MOST important safety precaution when considering prescribing eluxadoline for this patient?

Ask if she's had a cholecystectomy

What is the most appropriate next step in the management of this patient to monitor for potential long term complications of ulcerative colitis?

Screening for colorectal cancer

Which of the following would be MOST appropriate for a pharmacist to recommend for a 58 year old male with severe IBS D symptoms and a contraindication to eluxadoline due to a history of pancreatitis?

Begin treatment with rifaximin

What is the best strategy in this patient with anti infliximab antibodies?

Discontinue infliximab and start adalimumab

Which of the patient information below is LEAST important when applying the ROME criteria to his situation?

His symptoms are distressing and causing a decreased quality of life

All of the following are proposed etiologies for inflammatory bowel disease EXCEPT

Erythema nodosum

Which of the following drugs can only be used if the patient and physician both sign a written agreement provided by the manufacturer?

Alosetron

Based on the case details and colonoscopy findings, what is the most likely diagnosis?

Ulcerative Colitis

If she is started on Xifaxan and her diarrhea gets WORSE, which of the following drugs would be MOST appropriate to consider giving her?

An antibiotic

If the patient is started on IBSRELA, it would be MOST appropriate to tell the patient to take the medication

Before meals

A patient on Humira is not up to date with vaccines. Which vaccine is contraindicated?

Measles, mumps, rubella (MMR)

Which of the following drugs was temporarily removed from the market due to concerns over increased risk of cardiovascular ischemic events?

Tegaserod

Which drug is associated with bone marrow suppression, nausea, and vomiting because of its direct mechanism as an antimetabolite?

Azathioprine

Mesalamine is also known as which one of the following?

5-aminosalicylic acid

This patient's IBS would be best categorized as being

Moderate

What counseling point would be MOST appropriate for a pharmacist to provide to a patient starting rifaximin for IBS D?

Complete the full 14-day course, even if symptoms improve early

Which of the following changes would be appropriate to make to his maintenance regimen for Crohn's disease?

Stop infliximab and azathioprine and initiate vedolizumab

Of all the medications the patient is taking, which would be most likely to have a decrease in efficacy if the patient is started on tenapanor?

Enalapril

Based on the clinical presentation and colonoscopy findings (skip lesions, transmural inflammation), what is the most likely diagnosis?

Crohn's disease