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Describe what striated means in terms of muscle.
Muscle marked with long, thin parallel streaks
Describe what it means if a muscle is under voluntary control. Add an example. What muscle tissue(s) have voluntary control?
A muscle contracts with you consciously controlling it; ex. biceps; skeletal muscle
Describe what it means if a muscle is under involuntary control. Add an example. What muscle tissue(s) have involuntary control?
A muscle contracts without you consciously controlling it; ex. heart; smooth muscle and cardiac muscle
Describe Skeletal Muscle under a microscope
Very straight; no overlapping; nuclei are on sides of fibers; lots of striations
Describe Cardiac Muscle under a microscope
Fibers can connect; looks like branching trees
Describe Smooth Muscle under a microscope
Looks wavy; less defined; no striations
Skeletal Muscle: Is it striated? Voluntary? Location in body? Function in body?
Yes. Yes. Attached to bones. To produce movement; maintain posture and body position; generate heat
Smooth Muscle: Is it striated? Voluntary? Location in body? Function in body?
No. No. Inside walls of organs. Moves substances through the body; contracting; regulate size of passageways
Cardiac Muscle: Is it striated? Voluntary? Location in body? Function in body?
Yes; no; heart; to beat
Sliding Filament Theory (Simple definition)
The explanation of how muscles contract; myosin heads pull on actin filaments, causing them to slide toward the center of the sarcomere and shorten (contract) the muscle
Actin
A thin protein filament in muscle fibers; the track that myosin pulls on during contraction
Myosin
A thick protein filament with “heads” that bind to actin and pull to create movement
Tendon
A tough, fibrous connective tissue that attaches muscle to bone
Ligament
A connective tissue that attaches bone to bone at joints
Myofibril
Thread-like structures inside a muscle cell made of repeating sarcomeres. Contains actin and myosin
Muscle Cell
A long, cylindrical cell filled with myofibrils; contracts when stimulated
Fascicle
A bundle of muscle fibers grouped together
Epimysium
The outermost connective tissue layer surrounding the entire muscle
Perimysium
The connective tissue surrounding each fascicle
Endomysium
The connective tissue surrounding each individual muscle fiber
Sarcomere
The functional contractile unit of a muscle made of actin and myosin arranged in a repeated pattern
Neuron
A nerve cell that sends and receives electrical signals
Neurotransmitter
A chemical messenger released by neurons to send signals across synapses
Acetylcholine (ACh)
The neurotransmitter released at the neuromuscular junction to start a muscle contraction
Action Potential
An electrical impulse that travels along the neuron or muscle membrane, triggering contraction
T-tubule (Transverse Tubule)
Tiny tubes in muscle fibers that carry the action potential deep into the cell
Synapsis (Synapse)
The tiny gap between a neuron and the cell it communicates with
Troponin
A regulatory protein on actin that moves when calcium binds to it, allowing myosin to attach
Tropomyosin
A protein that blocks the myosin-binding site on actin until troponin shifts it
Neuromuscular Junction (NMJ)
The connection between a motor neuron and a muscle fiber where acetylcholine is released
Sarcolemma
The cell membrane of a muscle fiber
ATP
The energy molecule used in three key steps of contraction: Energizing myosin heads; Releasing myosin from actin; Pumping calcium back into the sarcoplasmic reticulum to end contraction
Describe the events that take place from the time you decide to move a muscle to your muscle contracting.
When your brain wants to move a muscle it sends an Action Potential signal down the spinal cord via neurons and goes to neurotransmitters called Acetylcholine (ACH), through a gap called the synapse to the sarcolemma t-tubule. Calcium gets called by the myosin to distract the tropomyosin and troponin, which are wrapped around actin to protect it from myosin. After they get distracted, myosin pulls actin together to contract the muscle.
Summary of Sliding Filament Theory
Myosin wants to grab actin, but it is usually protected by tropomyosin and troponin. They are easily distracted by calcium. When they get distracted by calcium, myosin can grab actin and pull it in (contracting). In order for myosin to release actin, and to “reset”, ATP is needed.
Origin
End of muscle that is attached to a bone that stays still during movement
Insertion
End of muscle that is attached to the bone that moves when the muscle contracts
Flexors; Think of an example
Muscles that decrease the angle between two bones; They bend a joint; Example: Biceps bending the elbow
Extensors; Think of an example
Muscles that increase the angle between two bones; They straighten a joint; Example: Triceps straightening the elbow
Prime Mover
The main muscle responsible for producing a specific movement; Does most of the work
Synergist
A muscle that assists the prime mover; Helps make the movement more stable or efficient
Antagonist; Think of an example
A muscle that opposes or reverses the action of the prime mover; Relaxes while the prime mover contracts; Example: Triceps is the antagonist when the biceps flex the arm
Contracting Muscle vs. Relaxing Muscle
A muscle is contracting when it is actively shortening or tightening to produce movement or maintain posture; A muscle is relaxing when it stops contracting and lengthens, allowing the opposite movement to occur.
What are the 7 ways that muscles are named?
Location, shape, size, direction of muscle fibers, # of origins, location of attachments, and action
6 rules of building muscles
1: Muscles have at least two points of attachment; Muscles cross at least one join. 2: Muscles shorten as they contract; Muscles can only pull. 3: Muscles have an origin and an insertion. 4: Flexion at a joint. 5: There must be prime movers, antagonists, and synergists. 6: Muscle fibers go in the direction of the pull of the muscle; do not put striations on tendons

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