PN-114-3 Urinary system

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Last updated 4:22 PM on 2/23/23
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Anatomy of the urinary system
\-2 kidneys

\-2 ureters channel urine to bladder

\-Bladder-muscular sac that stores urine

\-Urethra

\-Kidneys from urine, and the rest of the system eliminates it

\-Urine formation is to help remove potential toxic products from the blood
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Nephron
\-Functional and structural unit of the kidney

\-Urine is formed in approximately 1 million nephrons per kidney

\-Composted of a renal corpuscle and a renal tubule

\-Renal corpuscle consists of capillaries called glomerulus

\-Tubular system contains the PCT loop of Henle, DCTs, & collecting tubule
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Glomuler filtration
\-first step of urine production from nephrons. BP forces water and small solutes out of the glomeruli and into Bowman's capsules. This fluid is called renal filtrate. Renal filtrate then enters the renal tubules

\-Glomerular filtration rate (GFR)= the amount of blood filtered by the glomeruli in a set amount of time (Norm= 125L/min)
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tubular reabsorption
second step of urine production from the nephrons. is the recovery of useful materials (water and solutes) from the renal filtrate and their return to the blood
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tubular secretion
third step of urine production from the nephrons. substances are actively secreted from the blood into the filtrate "Kidneys are organs most responsible for maintaining the normal pH of blood and tissue fluid
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Normal urine amount
normal urinary output is 1000-2000 ml/24 hrs. Want to secrete 30 ml/hr. minimum
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Normal color of urine
straw or amber. If diluted will be a lighter color. If cloudy could indicate infection
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Normal specific gravity of urine
measure of dissolved materials in urine. Norm is 1.005 to 1.030
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normal pH of urine
range of urine is 4.6-8.0 with average of 6.0; diet has the greatest influence on urine pH
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normal constituents of urine
normal are urea, mineral salts, uric acid, creatinine, water. Abnormal \=sugar (ketones), pus, bacteria, acetone, albumin, blood, bile, nitrates
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Aging and the urinary system
\-With age, number of nephrons in the kidneys decrease often to half of the original number by age 70-80

\-Renal flow decreases by 50%

\-GFR decreases

\-Urinary bladder decreases in size and tone decreases

\-Increased frequency and nocturia

\-Older adults more prone to infections of the urinary tract

\-Meds are excreted through kidneys (slows the excretion of some meds as people age)
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Health history and the urinary system
\-age, gender, occupation, habits, medical history, urinary problems, new onset of symptoms, diet and fluid intake

\-Want a complete head to toe assessment

\-Pain in the flank or abdominal areas can be an indicator of renal problems or disease
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Daily weights and the urinary system
weight is best indicator for fluid balance in the body; with renal disease often have fluid imbalances. Weighed at same time each day on same scale
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Skin and the urinary system
inspected; can be yellow or gray cast with chronic disease. Presence of crystals on the skin is called uremic frost and is a late sign of waste products building up in the blood (uremia)
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Intake and output and the urinary system
patient with kidney disease will be on fluid restriction. I/O needs to be carefully monitored
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urinalysis
may be collected at any time of day, but first morning specimen is the best. Run it through machine to test for abnormalities. Clean perineum before collecting specimen. Collect urine mid-stream
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Urine culture and sensitivity
determines number of bacteria and identifies organism. Sensitivity determines the most effective antibiotic to use. Clean catch or cath.
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Urine creatinine clearance
best test of overall kidney function, amount of creatinine cleared from blood in 24 hours and determines renal function
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first step of urine creatinine clearance
At start, patient is directed to void and discard that urine
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Second step of urine creatinine clearance
Urine is collect for 24 hours in a large container. Keep refrigerated
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Third step of urine creatinine clearance
24 hours after test; patient needs to void again. This urine is added to collection container
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Fourth step of urine creatinine clearance
Lab collects serum creatinine during this 24 hour period
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BUN
blood, urea, nitrogen; waste products of protein metabolism- increased BUN can indicate kidney disease, renal failure can be affected by increased protein diet, dehydration, GI bleed (norm- 8-21 mg/dl)
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Serum creatinine
creatinine is waste product from muscle metabolism and is released into bloodstream (norm\=0.61-1.21 mg/dl- males; 0.51-1.11mg/dl- females). Good indicator of kidney function
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Serum electrolytes
Na+, K+, Ca+
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Cyastatin C
sensitive marker that reflects glomerular filtration rate (increases with impaired renal disease)
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KUB
x-ray of kidneys, ureter, bladder. Looks at size, shape, and stones
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IVP
intravenous pyelogram; IVP dye will outline kidneys and follow urine flow; checks kidney function. Enemas may be given the night before to empty colon
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retrograde pyelogram
small catch placed into ureter during a cystogram and dye injected; checks urine flow
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cystogram
cath inserted or cystoscope, dye is injected into bladder and evaluates bladder filling and emptying, distention, reflux, obstruction
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Renal ultrasound
diagnosis of congenital abscesses, hydronephrosis, tumors, kidney stones
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Renogram
radioactive substance injected to detect lesions. The amount of dye filtered and drained by the kidneys can be analyzed by a computer. Perfusion, function and drainage of the kidney can be determined
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cytoscopy
Surgical procedure that views the urethra, bladder, ureteral openings by scope. May remove small bladder tumors, polyps, stones, treat enlarged prostate or congenital abnormalities
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Nursing interventions for cystoscopy
Give post-op analgesics, encourage fluid intake, dysuria for 24 hours and initial voiding to be blood tinged. Measure urine output to detect retention from swelling of meatus
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Complications from cystoscopy
UTI, urine retention, bladder perforation
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Renal biopsy
\-Diagnose or provides information about kidney disease such as benign and malignant masses, causes of renal disease, transplant rejection

\-A CT scan or ultrasound is done first to locate the kidney for biopsy

\-A small section of the renal cortex is obtain for the lab either percutaneously or with small flank incision
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What patient's are not eligible for renal biopsy
bleeding tendencies, uncontrolled hypertension, or a solitary kidney
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Nursing considerations for renal biopsy
\-NPO 6-8 hrs. prior

\-No anticoagulants

\-Mild sedative given

\-Prone position with sandbag under abdomen

\-Monitor VS post-op

\-Monitor for bleeding 24 hours post-op

\-No heavy lifting for 2 weeks
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Urinary incontinence
involuntary leakage of urine; very common
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Management of urinary incontinence
\-Keep voiding diary

\-Refer to urologist to identify cause/treatment

\-Incontinence that cannot be treated is managed by the use of padding and absorptive products
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Stress incontinence
\-Involuntary loss of less than 50 ml of urine associated with increasing abdominal pressure during coughing, sneezing, laughing, or other physical activities

\-Common in women after child birth and menopause

\-Common in men with prostatectomy and radiation

\-Taught Kegel exercises to increase perineal muscle tone; do sets of 10 three times per day

\-Void at frequent intervals (q 2 hrs.)

\-Use urge inhibition techniques
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Urge incontinence
\-Involuntary loss of urine associated with abrupt and strong desire to voids

\-Patient usually cannot make it to the bathroom in time

\-Most common type of urinary incontinence in older adults

\-Taught Kegel exercises to increase perineal muscle tone; do sets of 10 3x per day

\-Use urge inhibition techniques
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Functional incontinence
\-Inability to reach the toilet because of the environmental barrier, physical limitations, loss of memory, or disorientation

\-Usually dependent on others and have no other urinary problems

\-Common in people who are often institutionalized

\-Teach patients to wear clothing that is not restrictive and easy to remove (sweat pants)

\-Provide appropriate urinary receptacles (commode, urinal)
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Overflow incontinence
\-Involuntary loss of urine associated with over-distention of the bladder

\-It occurs with acute or chronic urinary distention with dribbling of urine

\-Bladder is unable to empty normally despite frequent urine loss

\-Spinal cord injuries or enlarged prostate may cause overflow incontinence
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Total incontinence
\-Continuous and unpredictable loss of urine

\-Usually results from surgery, trauma, or malformation of ureter

\-Bladder training is ineffective

\-Patient is often neurologically impaired

\-Goal is to keep patient dry and clean
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Management of urinary retention
\-Urine retention is the inability to empty the bladder completely during attempts to void

\-Many factors can cause this

\-Can be acute/chronic

\-Can palpate bladder to see if distended

\-Use bladder scanner; scan assesses the volume of urine in the bladder

\-Painless; non-invasive

\-Normally bladder contains less than 50 ml after urination

\-Residue volume of 15-200 ml of urine indicates need for treatment of urine retention
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Indwelling catheters
\--Inset for various reasons

\--Short term use because of UTIs

\--Bacteria enter 1) around catheter up urethra into bladder 2) through outlet at the end of the collection bag contaminating urine; which goes back into bladder

\---Routine catheter care done

\---Encourage fluid intake

\---Maintain closed system

\---Secure to patients leg

\---Remove asap
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Intermittent catheterization
\--For pt. who is unable to void

\--Best for patients post-op, neurologic disorder, or urine retention

\--Reduces the risk of infection as long as the bladder is not allowed to overfill

\--Cath every 3 hours to empty bladder

\--Maybe taught to self-Cath at home
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suprapubic catheter
\-Used for long term situations

\-Indwelling Cath that is inserted through a surgical incision in the lower abdomen directly into the bladder

\-Need to keep the area clean and dry, changing dressing, keep it taped to prevent tension
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Urinary tract infection (UTI)
\-refers to the invasion of the urinary tract by bacteria

\-Urinary tract is sterile above the urethra
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Most common bacterial disease and Hospital acquired infection
UTI
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Lower UTI
urethritis, prostatitis, and cystitis
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Upper UTI
pyelonephritis and urethritis
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Path of UTI
caused most often by an ascending infection, starting at the external urinary meatus and progressing towards the bladder and kidneys
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What causes most UTI infections
E. Coli
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Risk factors for UTIs
\-Incomplete bladder emptying

\-Contamination in perineal and urethral areas

\-Instrumentation infection

\-Faulty valves causing reflux of urine

\-Previous UTIs

\-Female anatomic and genetic differences

\-Pregnancy

\-Age and urinary tract
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Signs and symptoms of UTI
\-Dysuria

\-Urgency

\-Frequency

\-Incontinence

\-Nocturia

\-Hematuria

\-Back pain

\-Cloudy, foul smelling urine

\-Fatigue (common in elderly)

\-Decline in mental status

\-Fever
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Urethritis
inflammation of the urethra that may result from a chemical irritant, bacterial infection, trauma, or STDs (gonorrhea and chlamydia)
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Common irritants leading urethritis
\-Bubble baths/salts common urethral irritants

\-Spermicidal agents
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Signs and symptoms of urethritis
frequency, urgency, dysuria, discharge from penis
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How is urethritis diagnosed?
UA or urine culture
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Treatment for urethritis
based on cause
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Pyridium
urinary analgesic, is often used to treat dysuria (turns urine orange)
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If sexually transmitted urethritis
partner must be treated
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Cystitis
inflammation and infection of the bladder wall
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cause of cystitis
bacteria, viruses, fungi, or parasites
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How do organisms cause cystitis
first grow in the perineal area then ascend into bladder
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Signs and symptoms of cystitis
dysuria, frequency, urgency, cloudy urine
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Types of Cystitis
complicated and uncomplicated
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How is cystitis diagnosed
urinalysis
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Cystitis treatment
uncomplicated cystitis-sulfa meds (Bactrim, Septra, or macrodantin)
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Nursing care for cystitis
patients must finish all prescribed meds regardless or symptoms, force fluids, and follow up with appointments
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pyelonephritis
infection of the renal pelvis, tubules, and interstitial tissue of one or both kidneys
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What causes pyelonephritis
Begins with colonization and infection of lower urinary tract; small abscesses throughput kidney and gross enlargement of the kidney
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What type of conditions are already existing to cause pyelonephritis
obstruction, strictures, stones
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Risk factors for for pyelonephritis
urological surgery, lymphatic infection, urinary stasis, and decreases immunity
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Signs and symptoms of pyelonephritis
fatigue, urgency, frequency, dysuria, flank pain, fever, chills, costovertebral tenderness pain, cloudy urine with RBCs, nitrates
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Diagnostic tests of pyelonephritis
will help differentiate pyelonephritis from cystitis. Urinalysis will show casts in kidney infection, have more than 100k colonies of bacteria
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Treatment for pyelonephritis
antibiotics, antispasmodic agents
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Nursing interventions for pyelonephritis
\-Force fluids 2-3 L (3k ml) per day

\-Avoid caffeine, alcohol

\-Empty bladder

\-Encouraging voiding q 3 hrs.

\-Avoid bubble baths and scented toilet paper

\-Wear cotton underwear

\-Drink cranberry juice to prevent bacteria from sticking on the walls of bladder

\-Administer antispasmodic agents and antimicrobial therapy for pain and discomfort from inflammation

\-Monitor urinary elimination

\-Educate- finish all prescribed meds to prevent recurrent infections
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Urethral structures
\-A narrowing of the lumen of the urethra caused by scar tissue

\-More prevalent due to rising incidence of STIs

\-Some result from trauma from insertion of catheters or surgical instruments, congenital abnormalities, or untreated gonorrhea

\-Diminished urinary stream and prone to UTIs

\-Usually seen in older men
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Treatment for urethral stricture
mechanical dilation; if continues surgical repair (urethroplasty) with stent
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renal calculi
\-Kidney stones made up of masses of crystals and protein that form when urine becomes supersaturated with a salt capable of forming solid crystals

\-Different types of stones

\-Diet and lifestyle can play a role in development

\-Stones may form in ureter or bladder, Stones less than 6 mm are readily passed in urine

\-Stones found in kidneys called nephrolithiasis
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Etiology/ signs and symptoms of renal calculi
\-Family history

\-Chronic dehydration

\-Infection

\-Dietary factors

\-Meds may cause stone formation

\-Excruciating flank pain and renal colic

\-Costovertebral tenderness

\-N&V

\-Diarrhea

\-Hematuria
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Prevention of renal calculi
\--Consult dietician

\--Encourage fluid intake

\--Encourage pt. to walk
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Complications of renal calculi
\--Renal calculi increases the risk for UTIs

\--If untreated can result in retention of urine and damage to kidney (hydronephrosis)
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Diagnostic tests for renal calculi
\-Helical CT without contrast

\-Urinalysis-hematuria

\-24 hour renal creatinine clearance-measures total urine

\-KUB-reveals most calculi

\-Ultrasound-identify stone in the renal pelvis, calyx, or ureter

\-Retrograde pyelography- identify the anatomic location of the stone
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Therapeutic measures for renal calculi
\-Most small stones are flushed out of body during urination

\-Can pass stone if 5mm or smaller

\-All urine must be strained to detect passage of stone; pain meds

\-Lithotripsy- use of sound, laser, or dry shock waves to break stone in small fragments

\-Surgery-endoscopic or open surgery
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hydronephrosis
\-Distention of the renal pelvis and calices

\-Results from untreated obstruction of urine flow in the urinary tract

\-Kidney enlarges as urine collects in the pelvis and kidney stones

\-Usually treatable
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Signs and symptoms of hydronephrosis
\-commonly develop UTIs, have frequency, urgency, dysuria, flank and back pain

\-Treatment=want to remove obstruction; insert indwelling catheter, surgery, stents, or nephrostomy tube insertion (make sure there are no kinks or clamps with tubes to allow urine to flow)
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Complications of hydronephrosis
UTI, urine retention, kidney failure
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Most common cancer of the urinary tract
bladder cancer
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Who primarily gets bladder cancer
Caucasian men around the age of 73
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How does bladder cancer start
\-Starts as benign growth on the bladder wall that undergoes cancerous changes

\-Usually begins in the inner lining of the bladder
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Causes of bladder cancer
Smoking, exposure to industrial pollution
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Signs and symptoms of bladder cancer
\--Usually painless hematuria

\--Bleeding is intermittent, which causes a delay in seeking treatment

\--As progresses; frank hematuria

\--Bladder irritability

\--Urine retention from clots

\--Fistula formation

\--Pelvic pain

\--Painful urination, inability to void
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Diagnostic tests for bladder cancer
\--Urinalysis

\--Urine culture

\--Cystoscopy

\--Cystoscopy

\--Transurethral biopsy

\--IV pyelogram
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Therapeutic measures for bladder cancer
\-Treatment depends on type and staging of bladder cancer

\-Chemo instilled into bladder through a catheter for small/confined tumors

\-Photodynamic therapy

\-Surgery

\-Incontinent urinary diversion-complete removal of the bladder; urine leaves the body in different manner. Will have an ileal conduit=involved surgery with 6-8 inch section pf the ileum or colon removed and used as conduit for urine. The remaining portions of the bowel are stitched back together. Ileal conduit contains mucus, so will normally secrete mucus strands. Must wear an ostomy appliance at all times to collect urine

\-Continent urinary diversion-done for patient convenience. Kock pouch; segment of the ileum that has been made into a reservoir for urine

\-The ureters are implanted into the side of the reservoir. A special nipple valve is constructed and is the passageway through which the patient inserts a Cath at 4-6 hour intervals to drain urine
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Nursing care for bladder cancer
\-Regular post-op care

\-Adequate urinary output and report any obstruction

\-Skin care around stoma

\-Patient teaching on how to care for Cath (urinary diversion) or by wearing an appliance

\-Body image disturbance may occur because of the change in body function
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Risk factors for kidney cancer
genetics, smoking, obesity, hypertension, years of kidney dialysis, and exposure to radiation, asbestos, and industrial pollution