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Solvents
Water or fluid in the body
Solutes
Particles that are dissolved or suspended in water or body fluids
Ph
Measures of hydrogen ion level in the blood and body fluids.
Adult male water %
60%
Adult female water %
55%
60-40-20 Rule
Total body H20 is 60% of body weight
Total ICF fluid is 40% of body weight
Total ECF fluid is 20% of body weight
Muscle tissue has more water than fat tissue
The two main systems that are responsible for fluid regulation
Heart and kidneys
Babies water %
78%
ICF- intracellular fluid
Contains 2/3 or 28L of total body H20
Fluid inside the cell.
Has a high concentration of total body water- trillions of cells in body
ECF- extra cellular fluid
Contains 1/3 or 14L of total body water
Fluid outside the cell
Has interstitial fluid (between the cells and outside the blood vessel) and intravascular fluid (blood or plasma inside the vessel)
Intravascular fluid
Plasma or blood inside vessels
92% water
Transcellular fluid
Includes CFS, pleural fluid, joint fluid, and eye fluid.
Fluid that is not intracellular but separate from plasma.
Plasma or intracellular fluid
92% water
Contains your salts, enzymes, clotting factors, red and white blood cells
Lymphatics
Helps keep body fluid in balance and defends against infection
Intravascular compartments 3L
ECF fluid, blood and plasma-liquid part of blood
About 55% of our blood is plasma
The remaining 45% are red, white blood cells, and platelets suspended in the plasma. Approximately 3L’s in the body
Capillary membrane
Barrier of endothelial cells, that have pores. They transport blood, oxygen, and nutrients between the blood and interstitial fluid.
It is where O2 and nutrients are exchanged for wastes and CO2
Interstitial fluid 11L
Below the capillary membrane
found in spaces between the cells and outside the blood vessels.
Helps bring oxygen and nutrients to cells and to remove waste products
Has very little proteins as they are large molecules and too large to pass through the capillary membranes.
Cell membrane
Semi permeable lipid layer
Separates the interior of the cell from the outside of the cells.
Also regulates materials entering and exiting the cell.
Intracellular fluid 28L
Contains the largest amount of fluid.
Water for example diffuses freely in out of the cell.
It also contains proteins, nutrients, and other electrolytes.
The most abundant electrolyte inside the cells are potassium
Outputs from the body
From the
Kidneys, lungs, feces, sweat, and skin (perspiration)
Active transport
Requires energy from ATP, to move electrolytes across the cell membrane from areas of low concentration to high concentration.
Ex: energy required to row upstream in a canoe
Diffusion
Passive movement of solutes or particles across a permeable membrane, from areas of higher concentration to lower concentration until equilibrium is reached.
Uses no energy
Osmosis
The movement of water through a selectively or semi permeable membrane.
Require no energy.
Colloid ontonic (osmotic) pressure
Blood contains albumin and other proteins known as colloids.
Osmotic pressure
Inward pulling force.
Helps move fluid from the interstitial space back into capillaries
Filtration
Fluid movement through a cell or blood vessel membrane because of hydrostatic pressure. (Blood pressure)
Does not require energy
Ex: kidneys and capillary beds.
Fluid homeostasis
Result of three processes
Fluid intake and absorption
Fluid distribution
Fluid output
Insensible water loss
Salivation, sweating, breathing, waste excretion, water or output cannot be measured.
3 assessments in assessing fluid balance
Clinical- mentation, skin turgor, thirsty, edema?
Intake/output
Review of blood chemistry and labs.
To every Celsius degree increase in body temp above normal a minimum of an additional 500mL of body fluids lost.