Theroux material - IBD

Ulcerative colitis mild proctitis initial therapy

5-ASA suppository

Ulcerative colitis mild left-sided colitis initial therapy

5-ASA enema +/- oral 5-ASA

Ulcerative colitis mild pancolitis initial therapy

oral 5-ASA +/- enema

Ulcerative colitis proctitis next-line therapy

tacrolimus or beclomethasone suppository

Ulcerative colitis left-sided colitis next-line therapy

oral budesonide

Ulcerative colitis pancolitis next-line therapy

oral corticosteroids

Ulcerative colitis mild proctitis remission therapy

5-ASA suppository

Ulcerative colitis mild left-sided colitis remission therapy

oral 5-ASA

Ulcerative colitis mild pancolitis remission therapy

oral 5-ASA

Ulcerative colitis moderate initial therapy

oral budesonide or oral 5-ASA

Ulcerative colitis moderate next-line therapy

systemic oral corticosteroids

Ulcerative colitis moderate remission therapy preferred biologic

infliximab with azathioprine

Ulcerative colitis severe initial therapy options

systemic corticosteroids, biologics, JAK inhibitors, S1P modulators

Curative non-pharmacologic treatment for ulcerative colitis

proctocolectomy

Crohn's disease medication to avoid

NSAIDs

Mild ileocecal Crohn's disease induction therapy

budesonide 9 mg daily

Mild colonic Crohn's disease treatment

sulfasalazine

Crohn's disease drug that should NOT be used (induction or maintenance)

oral mesalamine

Crohn's disease maintenance after steroid-induced remission

azathioprine OR 6-MP

Crohn's disease first-line therapy for fistulizing disease

infliximab