Tricarboxylic Acid Cycle (TCA)

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30 Terms

1
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What is the purpose of Lactate dehydrogenase (LHD) reaction

2
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How is LDH reaction regulated by TCA cycle activity

3
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What is the purpose of pyruvate dehydrogenase (PDH) complex

4
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How is PDH reaction regulated

5
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What are the required vitamins/cofactors of PDH complex

6
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What are the reactants and products of PDH complex

7
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What is the cellular localization of PDH complex

8
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What is the purpose of TCA cycle

9
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What is the cellular localization and tissue distribution of TCA cycle

10
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What are the enzymes involved in TCA cycle

11
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What are the reactants and products of TCA cycle

12
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How does carbohydrates contribute to generation of acetyl CoA

13
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How does fatty acids contribute to generation of acetyl CoA

14
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How does amino acids contribute to generation of acetyl CoA

15
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What is the biochemical/potential clinical consequences of TCA cycle enzyme deficiency in IDH tumors

16
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What is the biochemical/potential clinical consequences of TCA cycle enzyme deficiency in FH tumors

17
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What is the biochemical/potential clinical consequences of TCA cycle enzyme deficiency in SDH tumors

18
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What is oncometabolites

19
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What is TCA cycle products energy yield

20
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How does citrate regulate TCA cycle

21
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How does ATP/ADP regulate TCA cycle

22
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How does NADH/NAD+ regulate TCA cycle

23
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What is the role of TCA cycle intermediates as sources of reactants for biosynthetic pathways (cataplerosis)

24
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what is anaplerosis

25
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What are the major anaplerotic reactions of TCA cycle

26
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What is the central role of TCA cycle in connecting glycolysis

27
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What is the central role of TCA cycle in connecting gluconeogenesis

28
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What is the central role of TCA cycle in connecting oxidative phosphorylation

29
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What is the central role of TCA cycle in connecting fatty acid metabolism

30
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What is the central role of TCA cycle in connecting amino acid metabolism