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What is the purpose of Lactate dehydrogenase (LHD) reaction
How is LDH reaction regulated by TCA cycle activity
What is the purpose of pyruvate dehydrogenase (PDH) complex
How is PDH reaction regulated
What are the required vitamins/cofactors of PDH complex
What are the reactants and products of PDH complex
What is the cellular localization of PDH complex
What is the purpose of TCA cycle
What is the cellular localization and tissue distribution of TCA cycle
What are the enzymes involved in TCA cycle
What are the reactants and products of TCA cycle
How does carbohydrates contribute to generation of acetyl CoA
How does fatty acids contribute to generation of acetyl CoA
How does amino acids contribute to generation of acetyl CoA
What is the biochemical/potential clinical consequences of TCA cycle enzyme deficiency in IDH tumors
What is the biochemical/potential clinical consequences of TCA cycle enzyme deficiency in FH tumors
What is the biochemical/potential clinical consequences of TCA cycle enzyme deficiency in SDH tumors
What is oncometabolites
What is TCA cycle products energy yield
How does citrate regulate TCA cycle
How does ATP/ADP regulate TCA cycle
How does NADH/NAD+ regulate TCA cycle
What is the role of TCA cycle intermediates as sources of reactants for biosynthetic pathways (cataplerosis)
what is anaplerosis
What are the major anaplerotic reactions of TCA cycle
What is the central role of TCA cycle in connecting glycolysis
What is the central role of TCA cycle in connecting gluconeogenesis
What is the central role of TCA cycle in connecting oxidative phosphorylation
What is the central role of TCA cycle in connecting fatty acid metabolism
What is the central role of TCA cycle in connecting amino acid metabolism