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What does the lymphatic system do
Returns fluid leaked from blood vessels back into the blood vessels
What are the 3 parts the lymphatic system consists of
Lymphatic vessels
Lymph fluid in vessels
Lymph nodes
What are the lymphoid organs and tissues
Spleen
Thymus
Tonsils
Payers patches
MALT
Appendix
Red bone marrow
How many liters of fluid per day is forced out of blood vessels
3 liters
What is it called when fluid exits the blood vessels and washes around the tissues
Interstitial fluid
What fluid must be returned to the blood system and who accomplishes it
Interstitial fluid
Lymphatic system accomplishes
When interstitial fluid enters the lymph vessels what is the name change and what happens to it
From interstitial fluid to lymph fluid
It is cleaned up and returned to the blood system
The removal of interstitial fluid from tissue spaces begins where
At blind ended lymphatic capillaries
Where are blind ended lymphatic capillaries found
Weaving between lose connective tissue cells of the body
Where are lymphatic capillaries not found in
Bones
Teeth
Bone marrow
CNS
Lymphatic capillaries are very permeable due to what
The overlapping endothelial cells that form valve flaps in the walls of the vessels
which way to the valve flaps in the walls of the vessels open
Only inward
In lymphatic capillaries the endothelial cells are anchored to surrounding tissue by what
Collagen filaments
What do the collagen filaments in lymphatic capillaries prevent
Vessels from collapsing inwards due to interstitial pressure
Lymphatic capillaries can drain what from tissues of the body
Fluid
Proteins
Pathogens
Debris
Cancer cells
As lymph fluid runs through the lymph nodes what happens before reentering the blood system
It is cleaned up
What do lacteals do
They absorb digested fats from intestine turning clear lymph into milk fatty fluid called chyle which is delivered to the blood system
Lymphatic fluid flows through vessels from smallest to largest what is the order
Lymphatic capillaries
Collecting vessels
Trunks
Ducts
How many tunics do collecting vessels have
3
what are the differences in the tunics between the veins and lymph vessels
Lymph vessels have
Thinner walls
More valves
Anastomose more
Superficial vessels in the skin travel with what
Veins
Deep vessels of the trunk travel with what
Arteries
What is the bloody supply from in collecting vessels
Vasa vasorum
Collecting vessels form to fuse what
Trunks
What types of trunks do the collecting vessels form
Lumbar trunk
Bronchomediastinal trunk
Subclavian trunk
Jugular trunk
Intestinal trunk
The lymphatic trunks drain into what 2 large ducts in the thoracic system
Right lymphatic duct
Thoracic duct
What does the right lymphatic duct do
Drains lymph from right side of head, thorax and arm
What does the thoracic duct do
much larger duct that drains lymph from the rest of the body
The thoracic duct is formed from what
An enlarged sac called cisterna chyli
The lymphatic ducts empties lymph fluid into what circulation and what junction
Into venous circulation at the junction of internal jugular vein and subclavian vein
Characteristics of the transport of lymph
No pump
Low pressure in vessels causing sporadic fluid flow
Fluid flow of lymph depends on the action of what
Skeletal and respiratory muscles
Valves to prevent backflow
The pulsating action of adjacent arteries
What is lymphedema also known as
Lymphatic obstruction
What is lymphedema
A condition of localized fluid retention and tissue swelling caused by a compromised lymphatic system
Where do lymph nodes cluster along and what do they merge to form
Along lymphatic vessels and merge to form trunks
Where do lymph nodes mainly cluster in
Inguinal
Axillary
Cervical regions
What are the 3 functions of lymph nodes
They filter microorganisms and debris from lymph not delivered to blood system
Activate the immune system bc lymphocytes in lymph nodes monitor for antigens
Site of lymphocyte replication
What is the structure of lymph nodes
1in bean
Surrounded by dense fibrous capsule of connective tissue
Has strands of connective tissue that extend inward and divide node into compartments
Lymph nodes clean up your fluid using what
Lymphocytes and macrophages
lymphoid tissue can be scattered around the body in what
Organs and connective tissue
Large collections of lymph fluid are found in what
Lymph organs
What is the tissue type of lymphoid tissue
Reticular connective tissue
What is the functions of lymphoid tissue
Protect the body
Proliferation- rapid replication site for lymphocytes
Surveillance point for lymphocytes and macrophages
Where do macrophages live on
Reticular fibers
Where do lymphocytes circulate between
Blood system and reticular tissue
What are the primary lymphoid organs
Thymus and red bone marrow
What is the largest lymphoid organ
Spleen
The spleen is a site of what
Lymphocytes proliferation
Immune surveillance and response
What does the spleen house
Macrophages that remove debris
Stores broke down products of RBC- iron for later use
Is removal of spleen a problem? Why
Not a problem
Liver and bone marrow take over its functions
What is most active in childhood, stops growing in adolescence, and atrophy with age
Thymus
most thymic cells are what
Lymphocytes
What is the only lymphoid organ that doesn’t directly fight antigens