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major subdivisions of the brain
cerebrum, cerebellum, brainstem
cerebrum
two cerebral hemispheres which contain gyri (folds), sulci (grooves), and longitudinal cerebral fissure (big sulcus between hemispheres) connected by corpus callosum
gray matter of brain
- cortex (outer part) of cerebrum and cerebellum
- neurosomas
- dendrites
- unmyelinated axons
- synapses
white matter of brain
- deep in brain
- contain tracts made up of bundles of myelinated axons
Meninges of the brain
dura mater, arachnoid mater, pia mater
dura mater
tough, outer layer
dura layers within cranium
periosteal layer
meningeal layer
dural sinuses
superior sagittal sinus
transverse sinus
dural sheets that occupy spaces separating major parts of the brain
falx cerebi - between hemispheres
tentorium cerebelli - between cerebrum and cerebellum
arachnoid mater
transparent, middle layer, CSF, arachnoid granulations
pia mater
delicate, inner layer
lateral ventricles (2)
interventricular foramen
third ventricle (1)
cerebral aqueduct
fourth ventricle (1)
central canal of spinal cord
cerebrospinal fluid in ventricles
clear, colorless liquid
CSF production
choroid plexus (ependymal cells) within ventricles
CSF flow
within ventricles, down canals, and within subarachnoid space of the brain and spinal cord
CSF absorption
by arachnoid granulations back into blood at superior sagittal sinus
CSF provides
buoyancy, protection, & chemical stability
5 lobes of the cerebrum
frontal, parietal, occipital, temporal, insula
frontal lobe
(frontal bone to central sulcus) cognition, speech, and motor control
parietal lobe
(central sulcus to parieto-occipital sulcus) interprets signals of general senses and taste
occipital lobe
(parieto-occipital sulcus to occiptal bone) principal visual center
temporal lobe
(temporal bone to lateral sulcus) hearing, smell, learning, and memory
insula
(deep to lateral sulcus) taste, visceral sensation, and language
cerebral cortex
surface of hemispheres (40% of mass of the brain)
cerebral cortex cells
pyramidal cells (triangle shaped with apex pointing to brain surface) output neurons of cerebrum
vision
occipital lobe, primary visual cortex
hearing
temporal lobe and insula, primary auditory cortex
equilibrium
cerebellum, several brainstem nuclei
taste
parietal lobe, primary gustatory cortex
smell
temporal and frontal lobes, orbitofrontal cortex
precentral gyrus
primary motor cortex - exhibits somatotopy (a body map called motor homunculus)
postcentral gyrus
primary somatosensory cortex - exhibits somatotopy (a body map called sensory homunculus)
primary sensory cortex
first cortical region to receive input for that sense
primary motor cortex
issues projection fibers to distribute motor commands
association cortex
- Any cortical area that is not primary
- interpretation of sensations, thought, memory, and motor planning
- Prefrontal cortex
Language: Wernicke's area
posterior to lateral sulcus of left brain, recognition of written and spoken language
Language: Broca's area
inferior prefrontal cortex of left brain, speech
emotion
(several areas involved) amygdala outputs to hypothalamus and prefrontal cortex
cognition
(association areas of cortex) acquire and use knowledge
2 types of memory
procedural and declarative
memory
(limbic areas involved) amygdala creates emotional memories, hippocampus consolidates declarative long term memories
projection tracts
travel vertically to carry info between cerebrum and rest of body
commissural tracts
-Commissures cross between two hemispheres
-Corpus callosum is largest
association tracts
connect regions within same hemisphere
limbic system function
emotion and learning, contains gratification and aversion centers
prominent parts of limbic system
cingulate gyrus, hippocampus, amygdala
basal nuclei
deep masses of cerebral gray matter, involved in motor control
basal nuclei consists of
caudate nucleus, putamen, globus pallidus
Diencephalon
thalamus, hypothalamus, epithalamus
thalamus makes up...
4/5 of diencephalon
interthalamic adhesion
connects left and right thalami
Thalamus function
sensory gateway to the cerebral cortex - involved in sensation, memory, emotion, and some movement
Hypothalamus location
extends from optic chiasm to mammillary bodies
hypothalamus function
major control center of the autonomic nervous system and endocrine system
Epithalamus (pineal gland)
an endocrine gland
epithalamus (habenula)
relay from limbic system to midbrain
Epithalamus
forms the thin roof over the third ventricle
Brainstem
midbrain, pons, medulla oblongata
Midbrain posterior aspect
(tectum) tectal plate - 4 bulges consisting of superior and inferior colliculi
midbrain anterior aspect
- cerebral peduncles
- tegmentum w/ red nucleus
- substantia nigra (degenerates into parkinson's)
- cerebral crura anchor cerebrum to brainstem
cerebral aqueduct
passes through midbrain
- contains central gray matter
The midbrain gives rise to cranial nerves...
III and IV
pons anterior aspect
creates a large bulge
pons posterior aspect
contains peduncles that attach to cerebellum
pons
contain various tracts between spinal cord and the brain/cerebellum
The pons gives rise to cranial nerves...
V-VIII
medulla oblongata
extends from the pons to the foramen magnum of the skull (where it becomes the spinal cord)
important nuclei in medulla oblongata
cardiac center
vasomotor center
respiratory center
anterior surface bulges of medulla oblongata
Pyramids (medial) and Olives (lateral)
medulla oblongata gives rise to cranial nerves...
VIII, IX, X, XI
reticular formation
web of gray matter that runs through all levels of brainstem
reticular formation functions
somatic motor control
cardiovascular control
pain modulation
sleep and consciousness
habituation
cerebellum
cerebellar hemispheres (2)
- vermis in the center connecting them
arbor vitae of cerebellum
white matter
Deep nuclei of the cerebellum
gray matter
special neurons in cerebellum
purkinje cells
Alzheimer's disease (AD)
- Recent event memory loss
- Reduced attention span, disorientation
- Atrophy of gyri of cerebral cortex and hippocampus
- Neurofibillary tangles and senile plaques
Parkinson's disease (PD)
- Paralysis agitans
- Loss of motor function (tremors, shuffling gait, difficulty with movement sequences)
- Degeneration of dopamine-releasing cells from substantia nigra