Damage to the Host Cell

________ _____ are defined as virus-induced damage to the cell that changes its microscopic appearance

Cytopathic effects

It is common to find ______ _____, or compacted masses of viruses or damaged cell organelles, in the nucleus and cytoplasm

inclusion bodies

Why can examination of cells and tissues for cytopathic effects be important?

To Diagnose viral infections

One very common CPE is the fusion of multiple damaged host cells into single large cells containing multiple nuclei. These are called ________ or giant cells

syncytia

In the ________, cells are killed completely. They shrink, detach from the surface, and lyse

poliovirus

In _______ cells round up and partially detach from the surface. They tend to clump together

adenovirs

In ________ ________ _______ adjacent cells fuse together, forming a large cell with many nuclei.

Respiratory Syncytial Virus

The __________ can cause formation of inclusion bodies in either the cytoplasm or nucleus of the host cell.

Rabiesvirus