Week 12: Psychosis, Schizophrenia Spectrum and Other Psychotic Disorders

Schizophrenia

Severe psychological disorder characterized by disorganization in thought, perception, and behaviour

psychotic disorders

Characterized by unusual thinking, distorted perceptions, and odd behaviours

Psychosis

Severe mental condition characterized by loss of contact with reality

postive symptoms

The presence of abnormal behaviour

hallucinations, delusions, disorganized symptoms

What are the kinds of positive symptoms

grandeur

Delusions of _____ are when you think you’re someone very important even in the face evidence

persecution

Delusions of _____ are thinking others are out to get you

capgras syndrome

Thinking your loved ones have been replaced with someone else

Cotard’s syndrome

Thinking something is wrong with your body

negative symptoms

The absence of normal behaviours

Avolition

inability to initiate and persist in activities

alogia

absence of speech

anhedonia

lack of pleasure

flat/restricted affect

mask-like facial expression

Asociality

lack of interest in social interactions

schizophreniform disorder

Identical to schizophrenia but less than 6 months and can still conduct daily activities

schizoaffective disorder

Schizophrenia plus mood disorder

delusional disorder

Presence of delusions for one month or longer, behaviour not bizarre, less than 2 of criteria a (hallucinations, delusion, etc)

brief psychotic disorder

sudden, short-lived fully psychotic episode

attenuated psychosis syndrome

subthreshold psychotic-like condition that is recently worsening

Multiple gene variances

There is no one schizophrenia gene, but ______ ____ ______

cannabis

Gene-environment interactions are seen through ______ studies

DISC1

genetic linkage is with the _______ mutation

dopamine

Which NT system is too active

large ventricles and hypofrontality

_____ _____ and _________ are brain differences

Low SES

strong link between schizophrenia and ___ ___

insulin coma therapy, psychosurgery, electroconvulsive therapy

treatments for schizophrenia in the 30s