BMS 503- Immunization

What is the definition of immunization

the process by which a person or animal becomes protected against a disease

What Ig is a monomer, has 2 antigen binding sites, with the function of long-term immunity; memory antibodies; neutralizes toxins, opsonizes, fixes complement

IgG

What Ig is a dimer or monomer, has 4 or 2 antigen binding sites, is a secretory antibody; on mucous membranes

IgA

what Ig is a pentamer, has 10 antigen binding sites, and is produced at first response to antigen; can serve as B-cell receptor

IgM

What Ig is a monomer, has 2 antigen binding sites, and is a receptor on B cells

IgD

What Ig is a monomer, has 2 antigen binding sites, and is the antibody of allergy; worm infections

IgE

what’s a hapten

molecules too small to illicit an immune response

what antibody mechanisms enhance phagocytosis

neutralization, agglutination of microbes, precipitation of dissolved antigens

what antibody mechanism leads to cell lysis

activation of complement system

what is the injection of a killed or weakened infectious microorganism or piece of infectious microorganism in order to prevent the disease

vaccination/inolculation

what was the first human vaccine

small pox

what immunization is the injection of purified or antibody-containing- serum to provide rapid, temporary protection or treatment

passive

what immunization is an immune response triggered because of challenge with an immunogen (i.e. exposure to infectious agent or its antigens, vaccine, is long lasting)

active

in herd immunity, what does reducing the # of infectious hosts prevent

spread of an infectious agent and new genetic variants of the agent

what vaccine type is regarded as the most successful vaccine

live attenuated

what vaccine type contains only the antigenic parts of the pathogen

subunit

what’s an example of a subunit vx

Tdap