Cerebrospinal fluid

Cerebrospinal fluid

watery fluid derived from blood plasma; protects the brain by surrounding providing cushioning

role of choroid plexus in relation to CSF

CSF formed and secreted by choroid plexus into spaces of brain called ventricles

where is choroid plexus located

knots of capillaries

how many ventricles are in the human brain 

four fluid filled ventricles 

• 2 lateral, third and fourth 

Flow of CSF

1. CSF secreted by choroid plexus in each lateral ventricle

2. CSF flows through interventricular foramina into third ventricle

3. choroid plexus in third ventricle adds more CSF

4. CSF flows down cerebral aqueduct to forth ventricle

5. choroid plexus in fourth ventricle adds more CSF

6. CSF flows out to lateral apertures and one median aperture

7. CSF fills subarachnoid space and bathes external surfaces of brain and spinal cord

8. at arachnoid villi, CSF is reabsorbed into venous blood of dural venous sinuses

clinical correlation

expansion of ventricles (too much CSF in ventricles) characterizes the condition known as hydrocephalus → associated with autism and schizophrenia