Vaccination - USMLE Step 1

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8 Terms

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<ul><li><p><strong>A</strong>denovirus</p></li><li><p><strong>T</strong>yphoid</p></li><li><p><strong>P</strong>olio (sabin)</p></li><li><p><strong>V</strong>aricella</p></li><li><p><strong>S</strong>mallpox</p></li><li><p><strong>B</strong>CG</p></li><li><p><strong>Y</strong>ellow fever</p></li><li><p><strong>Inf</strong>luenza</p></li><li><p><strong>MMR</strong></p></li><li><p><strong>Ro</strong>tavirus </p></li></ul><p><strong>“A</strong>ttention <strong>T</strong>eachers!<strong> P</strong>lease <strong>va</strong>ccinate <strong>small</strong>, <strong>B</strong>eautiful,<strong> y</strong>oung <strong>inf</strong>ants with <strong>MMR ro</strong>utinely” </p><p></p>
  • Adenovirus

  • Typhoid

  • Polio (sabin)

  • Varicella

  • Smallpox

  • BCG

  • Yellow fever

  • Influenza

  • MMR

  • Rotavirus

“Attention Teachers! Please vaccinate small, Beautiful, young infants with MMR routinely”

What are the Live-Attenuated vaccines?

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Cellular and Humoral!

  • So you basically get life-long immunity

What kind of responses do live-attenuated vaccines induce?

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Mainly humoral, but technically also a weak cell-mediated response

What kind of response for killed or inactivated vaccines provide?

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<p>Hepatitis <strong>A</strong>, <strong>T</strong>yphoid (intramuscular), <strong>R</strong>abies, <strong>I</strong>nfluenza (intramuscular), <strong>P</strong>olio (sal<strong>K</strong>)</p><ul><li><p><strong>A TRIP </strong>could <strong>K</strong>ill you</p></li></ul><p></p>

Hepatitis A, Typhoid (intramuscular), Rabies, Influenza (intramuscular), Polio (salK)

  • A TRIP could Kill you

What are the inactivated (killed) vaccines?

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<p>*They target <strong>encapsulated </strong>bacteria</p>

*They target encapsulated bacteria

What are the subunit, recombinant, polysaccharide, and conjugate vaccines?

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  • Clostridium tetani

  • Cornybacterium diphtheriae

*ToxoiD → Tetanus and Diphtheriae

What are the toxoid vaccines?

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Sars-CoV-2!

What is the primary example of mRNA vaccine?

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Cellular and humoral immunity!

What response is induced from mRNA vaccines?