[cc mtap 1] plasma proteins

plasma proteins

• most frequently analyzed and divided into two groups: albumin and globulins

• inflammation increases acute phase reactants and decreases others

positive acute phase reactants

• upregulated

• concentrations increase during inflammation

negative acute phase reactants

• downregulated

• concentration decrease during inflammation

thansthyretin

other name for prealbumin

prealbumin

prealbumin

early indicator of poor nutritional status

transports retinol, thyroxine

prealbumin

2nd most predominant protein in csf. used only as a landmark to confirm that the specimen was likely csf

18-45 mg/dL

reference value of prealbumin

albumin

major plasma protein

protein present in highest concentration in plasma

liver

albumin is synthesized in the?

cystic fibrosis

albumin is a sensitive and highly prognostic marker of what disease?

negative acute phase reactant

albumin is a positive or negative apr?

active nephrotic syndrome

albumin is at its lowest value in?

not clinically significant

abnormally high albumin is ____________

analbuminemia

congenital absence of albumin

bisalbuminemia

two equal-intensity bands of albumin. additional band of albumin in this patient migrated more slowly than normal albumin into the a1 region.

globulin

• only about 1/3 of the total protein

• a1, a2, b, y fractions

early cirrhosis

globulin is elevated in? to to it balancing loss of albumin resulting to normal levels of total protein

2.3-3.5 mg/dL

reference value of globulin

TP-Albumin

formula to get globulin