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What defines chemically inert elements?
Atoms with complete valence shells, making them unreactive.
What are chemically reactive elements?
Atoms with incomplete valence shells that form chemical bonds to achieve stability.
What is the difference between a molecule and a compound?
A molecule involves the same atoms, while a compound involves different atoms.
What are ionic bonds?
Bonds formed by the complete transfer of electrons, resulting in charged ions.
What is a cation?
A positively charged ion that donates electrons.
What is an anion?
A negatively charged ion that accepts electrons.
What characterizes covalent bonds?
Electrons are shared between atoms to achieve stability.
What is a nonpolar covalent bond?
A bond where electrons are shared equally between atoms.
What is a polar covalent bond?
A bond with unequal sharing of electrons, resulting in partial charges.
What role do hydrogen bonds play?
They are weaker bonds that form between hydrogen atoms and electronegative ions.
What are inorganic compounds?
Compounds that do not contain carbon chains, such as water, acids, bases, and salts.
What are organic compounds?
Compounds that contain carbon covalently bonded, including carbohydrates, lipids, proteins, and nucleic acids.
Why is water considered a polar covalent molecule?
It has a partial positive charge on hydrogen and a partial negative charge on oxygen.
What is the significance of water as the universal solvent?
It is involved in all biochemical reactions occurring in the body.
What is the pH range of human blood?
The pH is maintained between 7.35 and 7.45.
What are acids in terms of hydrogen ions?
Substances that release hydrogen ions (H+), also known as proton donors.
What are bases in terms of hydrogen ions?
Substances that accept hydrogen ions (H+), also known as proton acceptors.
What is the function of buffers in the body?
They resist abrupt changes in pH by binding or releasing H+ ions.
What are monosaccharides?
Simple sugars with the general formula (CH2O)n, sweet and soluble in water.
What are disaccharides?
Composed of two hexose sugars, sweet and soluble in water, such as sucrose and lactose.
What are polysaccharides?
Long chains of glucose used for storage, known as starch in plants and glycogen in animals.
What are the two types of covalent bonds?
Nonpolar covalent bonds (equal sharing) and polar covalent bonds (unequal sharing).
What is the role of sodium chloride (NaCl) in water?
It dissociates into cations and anions, contributing to ionic balance in solutions.
What is the high heat capacity of water?
Water absorbs body heat, helping to regulate temperature.
What is the high heat of vaporization of water?
It allows water to evaporate from the body, cooling it down.
What are the four main types of organic compounds?
Carbohydrates, lipids, proteins, and nucleic acids.
What is dehydration synthesis?
A process where two molecules combine to form a larger molecule, releasing water as a byproduct.
What is hydrolysis?
A chemical process that splits a molecule by adding water.
What is glycogen?
A polysaccharide that serves as a form of energy storage in animals.
What are the four types of lipids?
Neutral fats, phospholipids, steroids, and eicosanoids.
What are neutral fats?
Also known as triglycerides, they consist of a glycerol backbone and three fatty acid chains.
What distinguishes saturated fats from unsaturated fats?
Saturated fats have single covalent bonds between carbon atoms and are solid at room temperature, while unsaturated fats have at least one double bond and are liquid.
What are lipoproteins?
Complexes of lipids and proteins that include very low density lipoproteins (vLDL), low density lipoprotein (LDL), and high density lipoprotein (HDL).
What is the role of aspirin in thromboembolic disorders?
Aspirin inhibits the cyclooxygenase enzyme, reducing the production of prostaglandins and thromboxanes, which are involved in blood clot formation.
What are amino acids?
The building blocks of proteins, each containing an amino terminal and a carboxyl terminal.
What are essential amino acids?
Amino acids that must be ingested through the diet.
What are the four structural levels of proteins?
Primary, secondary (alpha helix and beta pleated sheet), tertiary, and quaternary structure.
What is the difference between fibrous and globular proteins?
Fibrous proteins are extended and insoluble, providing structural support, while globular proteins are compact, soluble, and functionally active.
What is the structure of DNA?
DNA consists of a sugar-phosphate backbone with nitrogenous bases (adenine, thymine, guanine, cytosine) connected by hydrogen bonds.
What is the significance of LDL and HDL?
LDL is known as 'bad cholesterol' as it can lead to plaque buildup, while HDL is 'good cholesterol' that helps remove cholesterol from the bloodstream.
What is atherosclerosis?
A condition characterized by the buildup of plaque in the arteries, which can lead to heart attacks and strokes.
What is the function of eicosanoids?
Eicosanoids, derived from arachidonic acid, mediate various physiological reactions in the body.
What is the role of triglycerides in the human diet?
Triglycerides are the most abundant form of fat, providing energy and insulation.
What is the effect of trans fats on health?
Trans fats increase LDL levels, raising the risk of myocardial infarction and strokes.
Will have to know
a faticous atom - atomic number 13 what kind of chemcial molecule will it be so you have to put 2 then 8 then 3 -easier to gain 5 or lose ?
Cells are
Primarily water
Water polar covalent molecule
1 msot abundant 70% of body
2)Univerisal Solvent
3) high high capacity- buffer for body temp
4) High heaat of vaporization - water vaportaes from body using large amount of heat - cooling body
5) Cushoiniong body organs
Acids
release H + - proton donors
Bases
Accept h+ proton acceptors
Carbohydeates compounds covelant
Monosaccharides , Disaccharides , polysaccharides
Lipids Covalent link
Neutral fats- Triglyceride, steroils, eicosanoids
Proteins covalant link
Fibrous and globular proteins
Nucleic Acids covalent link
DNA, RNA
Carbohydrates Monosaccharides
hexose - Glucose, Furctose, Galactose
pentose 0 Deoxyribose, ribose
sweet and soluble
Carbohydrates Disaccharides
Matlose- Glucose Glucose
Sucrose -Glucose + Fructose
Lactose - Glucose and Galactose
soluble and sweet
Polysaccharides
Composed of logn chains fo glucose = storge form of glucose, aka stach in plants and glycogen in animals cells
not sweet insoluable inwater
Buffers
Will regulate ph in the blood by binding to h+, if the ph is to high the buffer will release H+ bringing ph to normal range
Out of range ph
No enzyme will work, homestatic imbalance, and reactions in body will halt
Lipids are...
Hydrophic and insoluble ein water
Types of lipids
Neutral fats , phosphlipids, steroids, eicosanoids
Nuetrals fat
glycerol backbone and 3 fatty acid chaains
Phospholipids
Composed of glycerol backbones, 2 fatty free acid chains attached
Steroids
Derived from cholesterol
Eicosanoids
Dereived from arachidonic acids
Neutral Fats
Triglycerides and triacyglycerol
most abundant form of fat in the human diet
aka fats when soil and oils when liquid
types of neutral fats
Saturated- single covalent bonds exist between all carbons in teh chain, solid at room temperates
increase LDL - myocardial infraction and strokes
Unsaturated - at least one double covalent bond - liquid at room temp - plant like olive oil
Types of Lipoproteins
Lipids and Proteins:
vLDL - very low denstiy lipoproteins
Low Density Lipoprpoeins = LDL bad cholesterol
high density lipoproteins HDL=. good cholesterol
Lipproteouns contains different kinds and amounts of lipids and proteins ..
- teh more protein the higher the density
The more lipid teh lower the density
each has different function
Cholesterol
waxy fat carried through the bloodstream by lipoproteins
Artherslcetoric plauge- plaque in arterieres
Glucose too much in body
stored as polysaccharides glycogen
Lipids Eicosanids
Adipose capsules..
Fats that help protect and holds as well as insulate organs
ex: kidneys lose too much weight the adipose will leave and kidneys fall from anatomical position and fail
Asprin
Limits and inhibits the Cyclooxgyenesnase WHIHCH STOP PROSTAGLANIDS AND THROMBOXANS leading to less clumpings from platelets
Proteins ..
aminos acids
Each amino acids has. termins that can act as a ... and a ..terminal that can aact as an ...
base, carboxyl, acid
AA are
ampthoertic molecules -- can act as acids and bases
essentail amino acids
these amino acids must be ingested in the diet
Non essential amino acids
syntehsized by the bodi via transmination reaction
You can tell cointaiminaton by virus and bacteria by
add beta helix helix and alpha pleated proteins
humans cells secondary structure true or false alpha pleated and beta helix
false
4 strucutral levels of proteins
primary structure- linear polypeptic chain indiciating the ty pe and position fo amino acids
Secondary strcuture 2 type
alpha helix coiled - coiled polypetide chain ehled together by hydrogen bonds
beta pleated - polypeptide chains linked side by side by huydrogen bonds
Tertiary structure
secoundary strcture, fold upon themselves to give a compact globule molecules , 3d structure held togehter by hydrogen bonds
Quatnery structure
2 or more polypeptide chains are held togetther by disulide bonds
2 classes of proteins
fibrous proteins
- insolulble in water
mechansism support and sensile strenght , main building material hence aka structural proteins
globular proteins
most likely tertiary/quatnrary
solbule inw ataer, sensitive to ph
chemically actival andmediaet all biochemical reactions hense aka functional proteins
Denaturation of globular protein
if very low dentnaturating unwrapes it and the active stite is exposed and substrate cannot bind
What is the basic structural and functional unit of all organisms?
A cell
What principle states that biochemical reactions in a cell are dictated by its subcellular structures?
The principle of complementarity of structure and function
What are the three main parts of a cell?
Plasma membrane, cytoplasm, and nucleus
What defines the boundary of a cell?
The plasma membrane
What is contained within the cytoplasm?
Cytoplasmic organelles
What is the function of the nucleus in a cell?
It contains genes that control the activities of the cell
What is the fluid mosaic model?
A model describing the plasma membrane's structure, where the lipid bilayer exhibits fluidity and membrane proteins are in constant flux
What are the two types of membrane proteins?
Integral proteins and peripheral proteins
What are transmembrane proteins?
Integral proteins that span the plasma membrane and are exposed on both surfaces
What is the role of cholesterol in the plasma membrane?
It stabilizes the plasma membrane and maintains its integrity
What is the function of glycoproteins in the plasma membrane?
They serve as identification tags recognized by other cells
What are tight junctions?
Fusions of integral proteins in adjacent cells that prevent the transfer of substances between them
What is a desmosome?
Linker proteins that hold adjacent cells together and prevent their separation
What is a gap junction?
A junction that allows rapid transfer of ions between cells, formed by connexons