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Nuremberg trials
Trials after WWII where Nazi doctors were punished for unethical human experiments. These trials led to new research ethics rules.
Nuremberg Code principles
Voluntary consent, avoid harm, participants can quit anytime, experiments must have scientific value, and researchers must stop if danger occurs.
Why research ethics matter
They protect participants, prevent abuse, and help keep science honest and trustworthy.
Tuskegee Syphilis Study
Researchers studied Black men with syphilis without telling them the truth and withheld treatment.
Ethical problems: deception, lack of informed consent, racism, and denying medical treatment.
Milgram Experiment
Participants thought they were giving painful electric shocks to someone to test obedience to authority.
Ethical problems: deception, emotional stress, and pressure to continue.
Stanford Prison Experiment
Students were assigned prisoner or guard roles in a simulated prison.
Ethical problems: psychological harm, abuse of power, and poor researcher oversight.
Declaration of Helsinki
International guidelines for ethical medical research that require informed consent, risk assessment, and protection of participants.
National Research Act
U.S. law that created research oversight systems and ethics review boards.
Belmont Report principles
Respect for persons (informed consent)
Beneficence (maximize benefits, reduce harm)
Justice (fair treatment)
Informed consent
Participants must be told the purpose, procedures, risks, benefits, and that they can withdraw anytime.
Deception
It is difficult because participants must normally know what the study involves, so deception must be justified and followed by debriefing.
Consent for minors / assent
Parents give consent, and the child gives assent (agreement to participate).
Protecting identity
Use anonymity, ID numbers, confidential records, and secure storage.
Coercion
When someone feels forced or pressured to participate.
Is payment coercion?
Usually not if the payment is reasonable and not extremely large.
Risk–benefit analysis
Researchers compare possible harms and benefits to decide if the study should happen.
Possible benefits
Scientific knowledge, helping society, medical progress, or participant insight.
Institutional Review Board (IRB)
A committee that reviews research to ensure it follows ethical guidelines.
Expedited review / minimal risk
Minimal risk means harm is no greater than everyday life; expedited review is a faster IRB review for low-risk studies.
Experiment characteristics
Manipulate an independent variable, measure a dependent variable, and control other variables.
True experiment vs quasi-experiment
True experiments use random assignment; quasi-experiments do not.
Confounding variables
Outside variables that affect results and must be controlled.
Factor and levels
A factor is an independent variable; levels are the different conditions.
Between-subjects design
Different participants are placed in different conditions.
Within-subjects design
The same participants experience all conditions.
Advantage of within-subjects
Controls individual differences and uses fewer participants.
Longitudinal study
Follows the same participants over a long period of time.
Cross-sectional study
Compares different age groups at the same time.
Matched-subjects design
Participants are paired based on similar characteristics before assignment.
Counterbalancing
Changing the order of conditions to prevent order effects.
All possible orders
Every possible order of conditions is used.
Incomplete counterbalancing
Only some orders are used.
Latin Square
A method where each condition appears once in each order position.
Internal validity
Whether the independent variable truly caused the change in the dependent variable.
External validity
How well results apply to real-world situations.
Construct validity
Whether the test measures the concept it claims to measure
Content validity
Whether a test covers all parts of the concept.
Criterion validity
Whether a measure predicts or matches an outcome.
Types:
Concurrent validity
Predictive validity
Threats to validity
Confounding variables, bias, demand characteristics, and selection problems.
Reliability
The consistency of a measurement.
Ways to test reliability:
Test–retest
Inter-rater reliability
Internal consistency
Beneficence and Nonmaleficence
Do good and avoid causing harm
Fidelity and Responsibility
Researchers must build trust and take responsibility.
Integrity
Researchers must be honest and accurate.
Justice
Research benefits and risks must be shared fairly.