panopto 11 collagen

molecular collagen

-triple helix 

-alpha chain 

-visible by electron microscopy 

• Chemical composition of collagen type I

-glycoprotein 

-glycine (every amino acid)

-repeating triplet (glycine-x-y)

X=proline 

y=4 hydroxyproline 

Important intra-molecular interactions

1. Rotational restrictions 

2. Interchain hydrogen bonding 

-galactose; glucose: carbohydrate attached to a single amino acid which is  5-hydroxylsine (uncommon)

height and width between collagen fibers

height: 67nm

width: 40nm

collagen type I

•  2(a1)  1(a2)

collagen type III

3 (a1)

• Interstitial collagen:

- type I, II, and III

-forms fibers