Functional Groups - Review

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31 Terms

1

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Phenol

pKa = 9-11

Acidic under physiological conditions

<p>pKa = 9-11</p><p>Acidic under physiological conditions</p>

2

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Sulfonamide

pKa = 9-10

Acidic under physiological conditions

<p>pKa = 9-10</p><p>Acidic under physiological conditions</p>

3

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Imide

pKa = 9-10

Acidic under physiological conditions

<p>pKa = 9-10</p><p>Acidic under physiological conditions</p>

4

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Alkylthiol

pKa = 10-11

Acidic under physiological conditions

<p>pKa = 10-11</p><p>Acidic under physiological conditions</p>

5

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Thiophenol

pKa = 6-7

Acidic under physiological conditions

<p>pKa = 6-7</p><p>Acidic under physiological conditions</p>

6

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N-Arylsulfonamide

pKa = 6-7

Acidic under physiological conditions

<p>pKa = 6-7</p><p>Acidic under physiological conditions</p>

7

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(N-)Acylsulfonamide

pKa = 5-6

Acidic under physiological conditions

<p>pKa = 5-6</p><p>Acidic under physiological conditions</p>

8

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Alkylcarboxylic Acid

pKa = 5-6

Acidic under physiological conditions

<p>pKa = 5-6</p><p>Acidic under physiological conditions</p>

9

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Arylcarboxylic Acid

pKa = 4-5

Acidic under physiological conditions

<p>pKa = 4-5</p><p>Acidic under physiological conditions</p>

10

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Sulfonic Acid

pKa = 0-1

Acidic under physiological conditions

<p>pKa = 0-1</p><p>Acidic under physiological conditions</p>

11

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Imine

pKa =3-4

Basic under physiological conditions

<p>pKa =3-4</p><p>Basic under physiological conditions</p>

12

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Arylamine

pKa = 4-5

Basic under physiological conditions

<p>pKa = 4-5</p><p>Basic under physiological conditions</p>

13

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Pyridines

pKa = 5-6

Basic under physiological conditions

<p>pKa = 5-6</p><p>Basic under physiological conditions</p>

14

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Alkylamines

pKa = 9-10 (primary), 10-11 (secondary)

Basic under physiological conditions

<p>pKa = 9-10 (primary), 10-11 (secondary)</p><p>Basic under physiological conditions</p>

15

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Amidine

pKa = 10-11

Basic under physiological conditions

<p>pKa = 10-11</p><p>Basic under physiological conditions</p>

16

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Guanidine

pKa = 12-13

Basic under physiological conditions

<p>pKa = 12-13</p><p>Basic under physiological conditions</p>

17

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Alkyl Alcohol

pKa =

__ under physiological conditions

<p>pKa = </p><p>__ under physiological conditions</p>

18

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Ether

Neutral

<p>Neutral</p>

19

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Ester

Neutral

<p>Neutral</p>

20

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Sulfonate Ester

Neutral

<p>Neutral</p>

21

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Amide

Neutral

<p>Neutral</p>

22

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Thioether

Neutral

<p>Neutral</p>

23

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Aldehyde

Neutral

<p>Neutral</p>

24

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Sulfoxide

Neutral

<p>Neutral</p>

25

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Nitrile

Neutral

<p>Neutral</p>

26

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Diarylamine

Neutral

<p>Neutral</p>

27

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Ketone

Neutral

<p>Neutral</p>

28

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Sulfone

Neutral

<p>Neutral</p>

29

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Carbamate

Neutral

<p>Neutral</p>

30

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Amine Oxide

Permanently charged across pH range

<p>Permanently charged across pH range</p>

31

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Quaternary ammonium

Permanently charged across pH range

<p>Permanently charged across pH range</p>