Hormone Activated Phospholipase C
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18 Terms
Identify step 1
Hormone (H) binds to a specific receptor
Identify step 2
The occupied receptor causes GDP-GTP exchange on Gqa
Identify step 3
Gqa with bound GTP, moves to PLC and activates it
Identify step 4
Active PLC cleaves PIP2 to IP3 and diacylglycerol
Identify step 5
IP3 binds to a specific receptor-gated Ca2+ channel, releasing sequestered Ca2+
Identify step 6
Diacylglycerol and Ca2+ activate protein kinase C at the surface of the plasma membrane
Identify step 7
Phosphorylation of cellular proteins by protein kinase C produces some of the cellular responses to the hormone
Identify 1
Phospholipase C (PLC)
Identify 2
PIP2
Identify 3
GTP
Identify 4
GDP
Identify 5
GDP
Identify 6
GTP
Identify 7
Diacylglycerol
Identify 8
Protein kinase C
Identify 9
IP3
Identify 10
Ca2+
Identify 11
Ca2+ channel
Note 
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