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Lesions
destroys tiny clusters of normal or defective brain cells to observe any effect on brain functions
EEG
measures electrical activity in the brain, uses electrodes
CT scan
uses x-ray to obtain detailed images of the body
PET scan
radioactive from of glucose injected, measures brain metabolism
MRI
radio-wave, strong magnets to measure structure of the brain
fMRI
tracks blood flow (oxygen), measure brain activity
serotonin
helps regulate mood, feel calm, focused, emotionally stable. Commonly used for depression and anxiety. Associated with htappiness and feeling good
too much serotonin
hallucinations
too little serotonin
depression, mood disorders, obsessive-compulsive disorder
dopamine
pleasure and rewards, causes to feel motivated, satisfied, excited. Enjoyable feeling that people will repeat behaviors. Addictive
too much dopamine
addiction, continue to engage in certain activities, schizophrenia
too little dopamine
parkinson’s disease, depression
norepinephrine
“fight or flight” response, alerts body to danger, increases bodily arousal, increases attention. Increases heart rate, breathing, blood pressure
too much norepinephrine
anxiety
too little norepinephrine
depression, mood disorders
gaba
calms and relaxes people, increases happiness, decreases anxiety, calms the CNS, reduces heart rate, blood pressure, breathing rate
too much gaba
overly sleepy, sedated, normal function is impaired
too little gaba
insomnia, anxious
endorphins
alleviate pain, lower stress, improve mood, enhance sense of well being
too much endorphins
body ignoring signals of pain, risking injury
too little endorphins
feeling significant pain
glutamate
excitatory neurotransmitter, important to memory, cognition, mood regulation
too much glutamate
overstimulate the brain, migraines, epileptic seizues
too little glutamate
insomnia, concentration problems, mental exhaustion
acetylcholine
motivation, arousal, attention, learning, memory, promote REM sleep, helps control certain physiological functions
too much acetylcholine
severe muscle spasms
too little acetylcholine
Alzheimer’s disease, dementia
subtance P
transmit pain signals to brain, help feel pain and react to it, regulate mood
too much substance P
chronic pain
too little substance P
reduced sensitivity to pain
adrenaline
stimulates nervous system to prepare the body for a quick response
oxytocinq
social bonding, child birth
melatonin
make us sleepy at night
ghrelin
hunger hormone
leptin
full hormone
ethical principles
do no harm, confidentiality, right to discontinue, informed consent, debriefing
positive skewed
mean > median > mode
negatively skewed
mean< median < mode