PHYS 225 G-Proteins

fast acting proteins with keys that open doors

Inotropic

slow acting proteins with keys that activates a process (opens door or activates enzyme)

metabotropic receptors

3 parts of G proteins

alpha, beta, gamma

G-proteins are __________ when GDP is attached.

inactive

G-proteins are _________ when GTP is attached

active

3 steps of G-protein pathway

1) _______ binds to _________.

2)_________ leaves, _________ binds.

3) _________/alpha leave and binds to ________.

-

hormone, receptor, GDP, GTP, GTP, protein

GTP/alpha bind to a protein because

1) _________ of an ________ channel

2) ________ activation

opening, ion, enzyme

_________ are found in cardiac muscle, retina, odor receptors, and blood vessels.

g-proteins

name secondary messengers for the following:

G-alpha S __________

G-alpha I ___________

G-alpha Q __________ and __________.

cAMP, cAMP, DAG, IP3

which two g-protein pathways are stimulatory?

alpha s, alpha q