disease detectives: the most awesome people in epidemiology

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sigmund freud was a cocaine-addled a-hole

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33 Terms

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Virginia Apgar

she created a test to assess neonatal status with 5 categories, predicting infant survival with the Apgar score

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Mantel and Haenszel

developed a statistical method for controlling confounding in case-control studies, allowing for improved comparisons between groups.

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Austin Bradford Hill

pioneered the randomized controlled trial concept and established a set of 9 criteria to assess principles for causality in epidemiology

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John Salk

an American pathologist that developed the polio vaccine (inactivated)

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Paul Louis Simmond

determined that plague was carried on fleas on the back of rats

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Joseph Lister

father of modern surgery, a brand of mouthwash (Listerine) was named after him

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Archie Cochrane

Scottish physician that analyzed efficacy and effectiveness (book from 1971) of interventions in RCTs, pioneer of evidence-based medicine, one of the fathers of modern clinical epidemiology

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John Snow

father of epidemiology, english physician & leader in development of anesthesia and medical hygiene, stomped on the miasma theory, used a dot map to solve the cholera outbreak in London, Broad Street (& violently ripped off the pump)

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Hippocrates

father of modern medicine, discovered that clubbing of the fingers is associated with lung disease/cancer, saved Athens from 430 BC plague (Peloponnesian war)

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John Graunt

father of demography (counting of people) and public health statistics, wrote the “Bills of Mortality”

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Lady Mary Wortley Montagu

introduced the British technique of smallpox inoculation (or variolation), controversy around her using smallpox sores to intentionally give someone a milder case of the disease

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Percival Pott

chimney dude in London. the first to demonstrate that cancer can be caused by an environmental carcinogen, well-know surgeon

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James Lind

found out citrus fruits were effective against scurvy, one of the first controlled clinical trials, navel-hygiene-typhus, used solar energy to clean water

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Edward Jenner

father of immunology, pioneered first vaccine (variolae vaccinae - pustules of the cow), using smallpox sores to make people immune to smallpox

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William Farr

british physicians that pioneered the quantitative study of morbidity and mortality. helped create first national vital statistics system and surveillance, developed a nosology from which the ICD (international developed

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Ignaz Semmelweis

Hungarian physician showed that hand washing would drastically reduce deaths among women who had just delivered babies in hospitals, pioneer of antiseptic procedures 

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Clara Barton

founder of red cross

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Louis Pasteur

 discovered vaccination, microbial fermentation, and pasteurization. Developed vaccines for cholera, anthrax, and rabies. Developed modern germ theory

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Joseph Lister

“Father of modern surgery” His antisepsis system is the basis of modern infection control. Applied science of Germ theory to surgery. carbolic acid (phenol) as sterilizer

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Robert Koch

further proof of germ theory; demonstrated that Mycobacterium tuberculosis was the causative agent for tuberculosis (creating the koch’s postulates) & showed that bacillus anthracis is the cause of anthrax.

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Walter Reed

US army surgeon that discovered & proved the causes of yellow fever (mosquitoes)

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Joseph Goldberger

linked poverty to disease; Found that Pellagra could be prevented with an improved diet.

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Alexander Fleming

discovered penicillin

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Bradford Hill

established Hill’s criteria and pioneered random controlled trials

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Salvador Mazza

controlled trypanosomiasis in America

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Albert Sabin

polish/american physician known for developing the oral polio vaccine, credited for the first polio vaccine WWII lieutenant colonel in US army medical crops & developed vaccine for japanese encephalitis

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Alice Stewart

studied radiation induced illness of workers in Hanford plutonium production plant & x-ray effect in pregnancy leading to childhood leukaemia

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Sir Richard Doll

proved correlation between smoking and lung cancer

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John Salk

Created the first Polio vaccine.

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Robert Gallo

scientist that shared discovery of the virus (HTLV, the only leukemia virus) that caused AIDS.

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Luc Mantagnier

received the Nobel Prize in Physiology or Medicine in 2008 for his team’s discovery that a retrovirus, HIV, was the cause of acquired immunodeficiency syndrome, or AIDS, thought SARS-COV-2 was a bioengineered virus

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David Fraser

discovered Legionnaires' disease in 1976, works for CDC

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Max Theiler

received Nobel Prize for developing vaccine against Yellow Fever