rho chi exam 4

Xanthine Oxidase is to uric acid synthesis as ___ is to Acetyl CoA synthesis

a) ACL

b) HMG

c) LDL

d) Geranyl PP

a) ACL

Torsades des Pointes arrhythmias are an adverse effect of treatment with

a) Propafenone

b) Digoxin

c) Amiodarone

d) Procainamide

c) Amiodarone

Desmopressin is selective for V1 receptors, and is indicated for type 1 diabetes:

a) First half is true, second half is true

b) First half is true, second half is false

c) First half is false, second half is true

d) First half is false, second half is false

d) First half is false, second half is false

Which of the following is major contraindication to allopurinol:

a) Azothiaprine

b) Amiodarone

c) Digoxin

d) Dofetilide

a) Azothiaprine

T/F: Lidocaine, a class 1b drug, has a greater effect when used during an MI 

• true

Which of the following are adverse effects associated with probenecid?

a) Increased level of statins

b) Hyperkalemia

c) Nephrolithiasis

d) Tendon rupture

c) Nephrolithiasis

Which of the following drugs directly increases the number of LDL receptors through inhibition of an enzymatic process?

a) Repatha

b) Ezetimibe

c) Fenofibrate

d) None of the above

a) Repatha

What is the effect of vasopressin administration on heart rate?

a) A direct positive chronotropic effect

b) A direct negative chronotropic effect

c) An indirect positive chronotropic effect

d) An indirect negative chronotropic effect

d) An indirect negative chronotropic effect

T/F: The transcription factor Rho assists in the upregulation of LDL receptors

• false

What is the advantage of finerenone over spironolactone?

a) It has a lower chance of causing hyperkalemia

b) It has a lower chance of causing gynecomastia

c) It has a lower chance of causing osteoporosis

d) It has no advantages over spironolactone

b) It has a lower chance of causing gynecomastia

T/F: Class 1c drugs are the drugs of choice for ventricular arrhythmias

• false

Which of the following drugs does NOT have an increase in uric acid levels as a side effect?

a) Torsemide

b) Niacin

c) Nexletol

d) Gemfibrozil

d) Gemfibrozil

Which of the following drugs has the same effect as Oxytocin?

a) Dinoprostone

b) Atosiban

c) Terbutaline

d) Nifedipine

a) Dinoprostone

Which of the following is not a concern with high doses of statins?

a) Edema

b) Rhabdomyolysis

c) Myalgia

d) Hepatotoxicity

a) Edema

Which of the following is not a Pleiotropic effect of statins:

a) Decreased adhesion molecules

b) Decreased cytokine production

c) Increased Thrombosis

d) Increased vasodilatory effects

c) Increased Thrombosis

SATA: Which of the following beta blockers are approved for the treatment of HF?

a) Metoprolol

b) Atenolol

c) Carvedilol

d) Bisoprolol

a) Metoprolol

c) Carvedilol

d) Bisoprolol

Acetazolamide will inhibit carbonic anhydrase, causing metabolic alkalosis

a) First half is true, but the second half is false

b) Both statements are correct

c) First half is false, but second half is true

d) Both statements are incorrect

a) First half is true, but the second half is false

T/F: Chronic use of Lasix will cause tinnitus

• false

Which of the following will block Na+ channels?

a) Ilbutilide

b) Flecanide

c) Praluent

d) Ditropan

b) Flecanide

Which of the following will inhibit cholesterol absorption from the intestine?

a) Zetia

b) Praluent

c) Questran

d) Edecrin

a) Zetia