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Genetics
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gene
A segment of DNA that contains the information required to produce a product that functions in the organism.
alleles
Different versions of a gene that have slight variations in the DNA sequence found in other alleles of the same gene.
transcription
The process that creates an RNA molecule from information stored in a gene.
translation
The process that uses the information in messenger RNA (mRNA) to synthesize a protein.
gene expression
The entire set of processes that results in using the information stored in a gene.
chromatin
The complex of DNA and histones that makes up a chromosome.
nucleosome
A group of eight histone proteins that has DNA wrapped around it.
histone proteins
Proteins that have an abundance of positively charged lysines and arginines in their primary structure, which interact with negative charges on the sugar-phosphate backbone of DNA to form nucleosomes.
Recessive Allele
An allele with a phenotype that does not appear in heterozygous individuals.
Dominant Allele
An allele with a phenotype that appears in heterozygous individuals.
Homozygous
Having two copies of the same allele for a gene.
Heterozygous
Having two different alleles for a gene.
Ploidy
The number of copies of each type of chromosome present
Mitosis
A process in eukaryotes that is responsible for distributing a copy of each chromosome to each daughter cell. It occurs after chromosomes have been replicated and prior to the physical division of the parent cell into two daughter cells.
M phase
The portion of the cell cycle when mitosis and cell division occur.
Interphase
The portion of the cell cycle when growth and DNA replication occur.
Prophase
The initial phase of mitosis, when replicated chromosomes condense and the nuclear envelope breaks down.
Metaphase
The middle phase of mitosis, when replicated chromosomes move to the middle of the cell.
Anaphase and Telophase
The late phases of mitosis, when sister chromatids separate and one of each type of chromosome ends up at either end of the parent cell, then nuclear envelopes re-form around each set of chromosomes.
Germ cells
Cells that directly give rise to sperm or eggs, or are sperm or eggs themselves. Germ cells undergo meiosis to produce haploid daughter cells.
Somatic cells
Cells that form the body, and that only undergo mitosis.
Meiosis
A process in eukaryotes that distributes one of each homologous chromosome pair to daughter cells, resulting in a halving of chromosome number.
Gamete
Cells that fuse to form a zygote. In many species, these are sperm and egg.
Zygote
A fertilized egg.
Maternal chromosome
Any chromosome inherited from the mother.
Parental chromosome
Any chromosome inherited from the father.
Crossing over and recombination
Physical exchange of DNA strands between non-sister chromatids during Meiosis I. Leads to recombinant chromosomes containing alleles from both maternal and paternal chromosomes.
Sexual reproduction
Production of offspring that is based on meiosis and fusion of gametes.
Asexual reproduction
Production of offspring that is based on mitosis.
Independent assortment
The observation that maternal and paternal homologs line up at random before separating at the end of Meiosis I, producing a wide array of possible combinations in daughter cells.