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Transduction
The process of converting incoming sensory stimuli into changes in membrane potential.
Receptor Potential
The change in membrane potential in a sensory receptor cell.
Polymodal Receptors
Sensory receptors that respond to more than one class of stimulus.
Dynamic Range
The range of stimuli intensities to which a receptor can respond.
Stereocilia
Hair-like structures in hair cells that detect mechanical changes.
Hyperpolarization
An increase in membrane potential difference, making the inside of the cell more negative.
Photoreceptor
A cell that captures light energy and converts it to electrical signals.
Ionic Channels
Proteins that allow ions to move across membranes, important in transducing signals.
Ciliary Photoreceptors
Photoreceptors that utilize a different mechanism for responding to light as compared to rhabdomeric photoreceptors.
Hormone Action
The specific effect a hormone has on target cells based on receptor binding.
Negative Feedback Loop
A process in which a system responds in a way that reduces the effect of the input signal.
G Protein-Coupled Receptors
A large family of receptors that sense molecules outside the cell and activate internal signal transduction pathways.
Thyroid-Releasing Hormone (TRH)
A hormone released from the hypothalamus that stimulates the release of thyroid-stimulating hormone (TSH).
Endocrine Regulation
Control of physiological functions through hormones released into the bloodstream.
Acromegaly
A disorder caused by excessive growth hormone, leading to enlarged bones and tissues.
Glycogenesis
The metabolic pathway in which glucose is converted to glycogen for storage.
Fovea Centralis
The part of the retina where visual acuity is highest due to a high concentration of cone photoreceptors.
Ligand-Gated Ion Channels
Ion channels that open in response to the binding of a ligand.
Anatomic Targeting
The direct delivery of hormones to specific tissues based on their proximity.
Photoreceptors
Cells sensitive to light, including rods and cones in the retina.
Corticotropin-Releasing Hormone (CRH)
A hormone that stimulates the anterior pituitary to release ACTH.
Oxytocin
A hormone that plays a key role in childbirth and lactation.
Insulin-like Growth Factor-I (IGF-I)
A hormone that plays an important role in growth and development.
Spermatogenesis
The process of sperm cell development.
Oogenesis
The process of egg cell development.
Homeostasis
The maintenance of stable internal physiological conditions.
Cyclic AMP (cAMP)
A secondary messenger involved in signal transduction pathways.
Steroid Hormones
Hormones that are lipophilic and can pass through cell membranes to bind to intracellular receptors.
Hormone Clearance
The process by which hormones are removed from circulation.
Receptor Dimerization
The process where two receptor molecules bind together, often in response to a ligand.
Neurohormones
Hormones released from neurons into the blood circulation.
Signal Transduction Pathways
Methods by which a cell responds to molecules outside of it and converts the signal into a functional response.
Mammalian Eye
The complex structure that includes various components involved in vision.
G-protein linked receptors
A type of receptor that transmits signals through the activation of G-proteins.
Endocrine Organs
Glands that secrete hormones into the bloodstream.
Prohormones
Inactive precursors to hormones that require cleavage to become active.
Insulin Receptors
Cell surface receptors that bind insulin and help regulate glucose uptake.
Adenylate Cyclase
An enzyme that converts ATP to cAMP upon stimulation by G protein-coupled receptors.
Mechanoreceptors
Sensory receptors that respond to mechanical pressure or distortion.
Chemoreceptors
Sensory receptors that respond to chemical stimuli.
Phototransduction
The process by which light is converted into electrical signals in the retina.
Neural Signal
An electrochemical signal transmitted by neurons.
Target Tissue
Specific tissues that respond to the hormone due to the presence of specific receptors.
Positive Feedback Mechanism
A process where the output enhances the input signal.
Ciliary Body
Part of the eye that controls the shape of the lens.
Posterior Pituitary
The part of the pituitary gland that releases hormones, including ADH and oxytocin, produced in the hypothalamus.
Gonadotropins
Hormones that stimulate the gonads, such as FSH and LH.
Pituitary Gland
An endocrine gland that controls various hormonal functions in the body.
Nuclear Hormone Receptors
Intracellular receptors that directly influence gene expression upon binding with their respective hormones.
Diabetes Mellitus Type 1
A chronic condition in which the pancreas produces little or no insulin due to autoimmune destruction of beta cells.