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Q: What is an endemic?
A: A disease that is always present in a particular area.
Q: What is an epidemic?
A: A sudden outbreak of a disease affecting many individuals at the same time.
Q: What is a pandemic?
A: A global epidemic spreading across continents.
Q: List human behaviors that increase risk of epidemics.
A: Exploration, globalisation, warfare, famine, poverty/overcrowding, poor sanitation, deforestation, wildlife contact.
Q: Why do outbreaks often emerge after environmental changes?
A: They allow infectious agents to expand beyond their original ecological niche.
Q: What percentage of human infections originate from animals?
60
Q: What percentage of new/emerging infections are zoonotic?
A: ~75%.
Q: Main routes of zoonotic spillover?
A: Wildlife farming, hunting, wet markets, exotic pets, domesticated animal contact.
List major routes of pathogen emergence.
Spillover from animals
Reappearing diseases (plague)
Spread to naïve populations (Zika)
Mutation/adaptation (influenza)
After natural disasters (cholera)
What bacterium causes plague & how is it transmitted?
A: Yersinia pestis; fleas on rodents.
Q: What bacterium causes cholera & how is it transmitted?
A: Vibrio cholerae; contaminated water/food.