Molecular Cell Biology - Protein Targeting Signals and Molecular Motors

Flashcards covering key protein targeting signals and molecular motors in Molecular Cell Biology.

What type of signal allows proteins to be transported into the nucleus?

Nuclear localization signal (NLS)

What is the destination of proteins tagged with a Mannose-6-phosphate (M6P) signal?

Lysosomal lumen

Which signal is used to direct proteins to the ER for translocation?

Signal sequence

How do proteins move from the Nucleoplasm to the Cytoplasm?

Via Nuclear export signal (NES)

What ensures proteins reach and remain in the Golgi?

ER exit signals and Golgi retention signals

What is the first step in moving a protein from the Golgi to the lysosome?

M6P Tag Addition

Which motor protein moves cargo toward the cell center?

Dynein

What direction does Myosin primarily move along the actin filaments?

Various directions (mainly toward the plus end)

What signal directs proteins to the secretory vesicle?

Involves signal peptides and vesicle sorting signals.

What type of targeting signal is required for targeting proteins to the plasma membrane?

Transmembrane domains and plasma membrane targeting signals.