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Tissue
A group of structurally similar cells performing the same function; the subject of histology.
Histology
The study of tissues.
Epithelial tissue
Avascular tissue that lines surfaces and cavities; protects, absorbs, secretes, excretes, filters, diffuses, and senses.
Avascular
Lacking blood vessels; epithelia rely on diffusion from underlying tissues.
Basement membrane
Anchors the basal surface of epithelium to the underlying connective tissue.
Fibers (fibrillar proteins)
Proteins such as collagen, alpha-keratin, myosin, and elastin that provide structural support in tissues.
Collagen
Strong, most abundant protein; forms fibers that give tensile strength.
Elastin
Elastic protein that allows tissues to recoil after stretching.
Alpha-keratin
Structural protein in hair, nails, and epidermis; contributes to toughness.
Ground substance
Semifluid matrix in connective tissue where cells and fibers reside.
Connective tissue
Tissue that supports, connects, or separates body parts; cells are embedded in an extracellular matrix.
Areolar
Loose connective tissue with fibroblasts, macrophages, and mast cells in a semifluid ground substance.
Adipose
Fat tissue composed of adipocytes that cushions, insulates, and stores energy.
Reticular
Network of reticular fibers forming the supporting framework in organs like the spleen and lymph nodes.
Dense regular connective tissue
Dense connective tissue with parallel collagen fibers; forms tendons and ligaments.
Dense irregular connective tissue
Dense connective tissue with collagen fibers in multiple directions; resists forces from many directions (e.g., dermis).
Cartilage
Rigid, avascular connective tissue with a gel-like matrix; types include hyaline, elastic, and fibrocartilage.
Hyaline cartilage
Cartilage that covers bone ends and supports bone growth; found at the ends of long bones.
Elastic cartilage
Cartilage with elastic fibers; can recoil after bending (external ear, epiglottis, auditory tubes).
Fibrocartilage
Strong cartilage that resists compression; found in intervertebral discs and joints.
Bone tissue
Rigid connective tissue with a mineralized matrix; two forms: compact and spongy.
Osteocyte
Mature bone cell located in a lacuna; maintains bone tissue.
Osteoblast
Bone-forming cell; responsible for forming new bone.
Osteoclast
Bone-resorbing cell; breaks down old bone tissue.
Diaphysis
Shaft of a long bone; houses the medullary cavity with yellow marrow.
Epiphysis
End of a long bone; articulating surface; site of red marrow and erythropoiesis.
Metaphysis
Region between diaphysis and epiphysis; contains growth region and helps transfer loads.
Epiphyseal plate
Growth plate; cartilaginous region that allows bone lengthening before puberty.
Ligament
Connects bone to bone; dense elastic tissue; example: ACL.
Tendon
Connects muscle to bone; dense fibrous tissue.
Blood
Fluid connective tissue with plasma, red and white blood cells, and platelets; transports gases and nutrients.
Plasma
Liquid component of blood; carries water, salts, enzymes, nutrients, and proteins.
Red blood cells (RBCs) / erythrocytes
Cells that transport oxygen via hemoglobin.
White blood cells (WBCs) / leukocytes
Immune cells that defend against infection; includes lymphocytes, monocytes, and granulocytes.
Platelets (thrombocytes)
Cell fragments that help stop bleeding; originate in bone marrow.
Lymph
Colorless fluid carrying white blood cells; part of the lymphatic system.
Skeletal muscle
Voluntary, striated muscle with multiple nuclei; organized into fascicles.
Smooth muscle
Involuntary, non-striated muscle; single nucleus; lines walls of hollow organs.
Cardiac muscle
Involuntary, striated muscle with intercalated discs; fatigue-resistant.
Intercalated discs
Cell junctions in cardiac muscle that coordinate rapid conduction between cells.